Three-dimensional reconstruction of fracture callus morphogenesis

…, YM Alkhiary, EA Krall, FH Nicholls… - … of Histochemistry & …, 2006 - journals.sagepub.com
Rat and mouse femur and tibia fracture calluses were collected over various time increments
of healing. Serial sections were produced at spatial segments across the fracture callus. …

Osteogenic effects of traumatic brain injury on experimental fracture-healing

M Boes, M Kain, S Kakar, F Nicholls, D Cullinane… - JBJS, 2006 - journals.lww.com
Background: Heterotopic bone formation has been observed in patients with traumatic brain
injury; however, an association between such an injury and enhanced fracture-healing …

Ligament augmentation for prevention of proximal junctional kyphosis and proximal junctional failure in adult spinal deformity

…, JK Scheer, D Lau, JA Osorio, F Nicholls… - … of Neurosurgery: Spine, 2018 - thejns.org
OBJECTIVE Proximal junctional kyphosis (PJK) is a well-recognized, yet incompletely defined,
complication of adult spinal deformity surgery. There is no standardized definition for PJK, …

Factors associated with the development of and revision for proximal junctional kyphosis in 440 consecutive adult spinal deformity patients

FH Nicholls, J Bae, AA Theologis, MS Eksi, CP Ames… - Spine, 2017 - journals.lww.com
Study Design. Retrospective review of prospectively collected data. Objective. The aim of
this study was to examine which radiographic parameters and surgical strategies are most …

The clinical correlation of the Hart-ISSG proximal junctional kyphosis severity scale with health-related quality-of-life outcomes and need for revision surgery

D Lau, H Funao, AJ Clark, F Nicholls, J Smith, S Bess… - Spine, 2016 - journals.lww.com
Study Design. Retrospective analysis of prospective data. Objective. Evaluate the utility of
the Hart-International Spine Study Group proximal junctional kyphosis severity scale (Hart-…

Genetic variation in the patterns of skeletal progenitor cell differentiation and progression during endochondral bone formation affects the rate of fracture healing

…, C Price, LJ Silkman, FH Nicholls… - Journal of Bone and …, 2008 - academic.oup.com
These studies examined how genetic differences that regulate architectural and bone
material properties would be expressed during fracture healing and determine whether any of …

Fractures after removal of spinal instrumentation: revisiting the stress-shielding effect of instrumentation in spine fusion

…, CP Zafeiris, KC Thomas, P Lewkonia, FH Nicholls… - World neurosurgery, 2018 - Elsevier
Background Many practicing spine surgeons believe that instrumentation can be removed
during revision surgery in successful posterolateral or anterior spinal fusions, confirmed by …

L5-S1 pseudoarthrosis rate with ALIF versus TLIF in adult spinal deformity surgeries: A retrospective analysis of 100 patients

…, M Oppermann, N Evaniew, A Soroceanu, F Nicholls… - World Neurosurgery, 2023 - Elsevier
Objective Lumbosacral pseudoarthrosis is a common complication following adult spine
deformity (ASD) surgery. This study assessed the reoperation rate for L5-S1 pseudoarthrosis in …

Mechanical complications in adult spinal deformity surgery: can spinal alignment explain everything?

…, S Aldebeyan, A Aoude, G Swamy, FH Nicholls… - Spine, 2022 - journals.lww.com
Study Design. Cohort study. Objective. Our goal was to verify the validity of the global alignment
and proportion (GAP) score, SRS-Schwab, and Roussouly theoretical apex of lordosis in …

Effects of radiation and surgery on healing of femoral fractures in a rat model

F Nicholls, K Janic, P Filomeno, T Willett… - Journal of …, 2013 - Wiley Online Library
Management of soft tissue sarcoma involves multimodality treatment, including surgery and
radiotherapy. Pathologic fracture of the femur after such treatment in the thigh is one serious, …