John A. Baron, Bernard F. Cole, Robert S. Sandler, Robert W. Haile, Dennis Ahnen, Robert
Bresalier, Gail McKeown-Eyssen, Robert W. Summers, Richard Rothstein, Carol A. Burke, …

ContextLaboratory and epidemiological data suggest that folic acid may have an antineoplastic
effect in the large intestine.ObjectiveTo assess the safety and efficacy of folic acid …

The efficacy and safety of 4-g 5-aminosalicylic acid enemas were assessed in 153 patients
with ulcerative colitis involving up to 50 cm of distal colon. Seventy-six patients received …

Background & Aims Methotrexate and infliximab are effective therapies for Crohn's disease (CD).
In the combination of maintenance methotrexate-infliximab trial, we evaluated the …

Patients with inflammatory bowel disease (IBD) have an increased risk of vascular complications.
Thromboembolic complications, both venous and arterial, are serious extraintestinal …

Background Long-term corticosteroid therapy for Crohn's disease is associated with important
types of morbidity, such as osteoporosis. Safe and effective alternative treatments are …

Restorative proctocolectomy with ileal-pouch anal anastomosis (IPAA) is the operation of
choice for medically refractory ulcerative colitis (UC), for UC with dysplasia, and for familial …

Background and aims: The classification of Crohn’s disease (CD) is usually determined at
initial diagnosis and is frequently based on ileocolonoscopic and cross-sectional imaging data…

Background: The SEDASYS System (SS) is an investigational, computerassisted, personalized
sedation system intended to provide endoscopist/nurse teams an “on-label” method to …

A 33-year-old woman developed subacute hepatic necrosis after several months of ingestion
of Chaparral Leaf, an herbal product. Symptoms first appeared 3 months after she began …