Background: Preclinical data suggest that metformin may reduce breast cancer incidence
and improve cancer prognosis. However, the current evidence in observational studies is …

Purpose The TAX 327 study compared docetaxel administered every 3 weeks (D3), weekly
docetaxel (D1), and mitoxantrone (M), each with prednisone (P), in 1,006 men with …

Objective A high frequency of infections complicating rheumatoid arthritis (RA) has been
described in reports of case series. This retrospective longitudinal cohort study was undertaken …

… Discrepancies were resolved by consensus or adjudication by a third investigator (GR
Pond). General characteristics were extracted, including publication year, tumor type, treatment …

Objective Patients with rheumatoid arthritis (RA) have been shown to have an increased
susceptibility to the development of infections. The exact causes of this increased risk are …

Objective To determine time trends in the epidemiology of rheumatoid arthritis (RA) in a
population‐based cohort. Methods An inception cohort of residents of Rochester, Minnesota ≥…

Background Adjuvant radiotherapy is prescribed after breast-conserving surgery to reduce
the risk of local recurrence. However, radiotherapy is inconvenient, costly, and associated …

Surface coal mining with valley fills has impaired the aquatic life in numerous streams in the
Central Appalachian Mountains. We characterized macroinvertebrate communities from …

… Eckhardt S, Siu L, Clark G, et al. The continual reassessment method (CRM) for dose …
Yuan Y, Yin G. Sequential continual reassessment method for twodimensional dose finding. …

Background: Nonradiolabeled iothalamate clearance is an accurate way to determine
glomerular filtration rate (GFR). Objectives of this study are to define the normal range of …