Myelin water imaging (MWI) promises to be invaluable in understanding neurological
diseases like MS. However, a limitation of MWI is signal to noise ratio. Recently, a number of …

The ability to measure myelin in vivo has great consequences for furthering our knowledge
of normal development, as well as for understanding a wide range of neurological disorders. …

We have used the CPMG pulse sequence to measure proton T 2 values and water content
in spinal cord and brain samples from Hartley guinea pigs inoculated to produce …

Remyelination is limited in the majority of multiple sclerosis (MS) lesions despite the presence
of oligodendrocyte precursor cells (OPCs) in most lesions. This observation has led to the …

Central nervous system (CNS) tissue was studied by immunocytochemistry and electron
microscopy from three cases of multiple sclerosis (MS) in which evidence of ongoing myelin …

Background: The pathological basis of diffusely abnormal white matter (DAWM) in multiple
sclerosis (MS) has not been elucidated in detail, but may be an important element in disability …

Evidence has shown that excitotoxicity may contribute to the loss of central nervous system
axons and oligodendrocytes in multiple sclerosis and experimental autoimmune …

Damage to myelin is a key feature of multiple sclerosis ( MS ) pathology. Magnetic resonance
imaging ( MRI ) has revolutionized our ability to detect and monitor MS pathology in vivo. …

Multi-echo T 2 measurements are invaluable in studying brain pathology in multiple
sclerosis (MS). In addition to information about myelin water and total water content, the T 2 …

Objective To analyze the texture of T2‐weighted magnetic resonance imaging (MRI) of
postmortem multiple sclerosis (MS) brain, and to determine whether and how MRI texture …