An increasing number of studies are describing potential uses of circulating tumour DNA (ctDNA)
in the care of patients with colorectal cancer. Owing to this rapidly developing area of …

Purpose Prognostic and predictive factors are well established in early-stage breast cancer,
but less is known about which metastatic sites will be affected. Methods Patients with early-…

Background Early cancer detection could identify tumors at a time when outcomes are
superior and treatment is less morbid. This prospective case-control sub-study (from …

Purpose The risk of local and regional relapse associated with each breast cancer
molecular subtype was determined in a large cohort of patients with breast cancer. Subtype …

… A 24-h urinary 5-HIAA analysis should be performed for all patients with a small intestinal
primary NET, as well as those with symptoms suggestive of the carcinoid syndrome (Table 2). …

Importance Single-agent immune checkpoint inhibition has not shown activities in advanced
refractory colorectal cancer (CRC), other than in those patients who are microsatellite-…

… Gelmon, Brian Norris, Hagen Kennecke, Stephen Chia, Kathleen Pritchard, Andrea Eisen,
Ted Vandenberg, Marianne Taylor, Eric Sauerbrei, Moshe Mishaeli, David Huntsman …

Background Insulin-like growth factors (IGF-1 and IGF-2) bind to the IGF-1 receptor (IGF-1R),
increasing cell proliferation and survival. Ganitumab is a monoclonal IgG1 antibody that …

Background Undertreatment has been frequently reported in the elderly cancer patient
population. For this reason, we aimed to characterize adjuvant chemotherapy (AC) use among …

BACKGROUND Adjuvant chemotherapy (AC) is frequently considered in patients with stage
II colon cancer who are considered to be at high risk. However, to the authors' knowledge, …