Background Observational studies have suggested that accelerated surgery is associated
with improved outcomes in patients with a hip fracture. The HIP ATTACK trial assessed …

BACKGROUND: Spinal reconstructive surgery in adults can be associated with significant
blood loss, often requiring allogeneic blood transfusion. The objective of this randomized, …

To determine the influence of time from injury to surgery on neurological recovery and length
of stay (LOS) in an observational cohort of individuals with traumatic spinal cord injury (tSCI)…

10.7554/eLife.44530.001 Two-dimensional (2D) human skeletal muscle fiber cultures are ill-equipped
to support the contractile properties of maturing muscle fibers. This limits their …

An interdisciplinary expert panel of medical and surgical specialists involved in the management
of patients with potential spinal cord injuries (SCI) was assembled. Four key questions …

In prior analyses of the effectiveness of methylprednisolone for the treatment of patients with
acute traumatic spinal cord injuries (TSCIs), the prognostic importance of patients' …

Placenta growth factor (PlGF), a homodimeric glycoprotein that is homologous to vascular
endothelial growth factor (VEGF), is mitogenic to endothelial cells and protects trophoblast …

Objective To analyze relations among injury, demographic, and environmental factors on
function, health-related quality of life (HRQoL), and life satisfaction in individuals with traumatic …

Clinical trials of therapies for acute traumatic spinal cord injury (tSCI) have failed to
convincingly demonstrate efficacy in improving neurologic function. Failing to acknowledge the …

Three-dimensional (3D) in vitro models of human skeletal muscle mimic aspects of native
tissue structure and function, thereby providing a promising system for disease modeling, drug …