Reductive amination plays a paramount role in pharmaceutical and medicinal chemistry
owing to its synthetic merits and the ubiquitous presence of amines among biologically active …

Studies of vitamin D and calcium for fracture prevention have produced inconsistent results,
as a result of different vitamin D status and calcium intake at baseline, different doses and …

Background Bone metastases (BM) are common in NSCLC patients. Despite some potential
positive effects of bone-targeted therapies, their use in NSCLC is infrequent, which may …

Background & aims Agents that induce an immune response against tumors by altering T-cell
regulation have increased survival times of patients with advanced-stage tumors, such as …

Purpose: Adoptive cell therapy with autologous tumor-infiltrating lymphocytes (TIL) has shown
promising results in metastatic melanoma patients. Although objective response rates of …

Reservoir containing water, oil and gas. The figure shows the fluid distribution in a typical
reservoir before production or injection begins. Above the free-oil level, water saturation will be …

Context: Serum 25-hydroxyvitamin D [25(OH)D] may influence serum PTH and other parameters
of bone health up to a threshold concentration, which may be between 25 and 80 nmol/…

Poor vitamin D status is common in the elderly and is associated with bone loss and
fractures. The aim was to assess worldwide vitamin D status in postmenopausal women with …

New analytic solutions are presented in real time and as Laplace transforms for horizontal
wells in reservoirs bounded at the top and bottom by horizontal planes. Two types of boundary …

The evidence on the association between vitamin D deficiency and fracture incidence is
contradictory. Therefore, the objective of this study was to examine whether low serum 25-…