The use of liquid biopsies for cancer detection and management is rapidly gaining prominence
1 . Current methods for the detection of circulating tumour DNA involve sequencing …

Cancer therapies that target epigenetic repressors can mediate their effects by activating
retroelements within the human genome. Retroelement transcripts can form double-stranded …

Drug-resistant cancer cells represent a major barrier to remission for patients with cancer.
Here we show that drug-induced metabolic perturbation and epigenetic states enable evasion …

During cancer initiation and progression, the somatic epigenome is broadly reprogrammed.
This reprogramming can be a consequence of several processes, including altered …

… Kirsty Taylor, # 1 Helen Loo Yau, # 2 Ankur Chakravarthy, 2, 3 Ben Wang, 4, 5 Shu Yi Shen,
3 Ilias Ettayebi, 2 Charles A Ishak, 2, 3 Philippe L Bedard, 1 Albiruni Abdul Razak, 1 Aaron R …

We demonstrate that DNA hypomethylating agent (HMA) treatment can directly modulate the
anti-tumor response and effector function of CD8 + T cells. In vivo HMA treatment promotes …

… Marhon and Ilias Ettayebi performed all bioinformatics analyses. Fabíola Attié de Castro
and … Ilias Ettayebi performed also the cell line knock-out and gene expression experiments. …

Editors of the AACR Journals reviewed recently published content to identify hot topics across
the entire portfolio. This collection focuses on triple-negative breast cancer and highlights …

Nucleic acid sensing is a central mechanism for innate immune defense against foreign
molecules that culminates with an activation of interferon signaling pathways. This involves …

Abstract In the Supplementary Information of this Article, owing to an error during the
production process, most of the gel images in Supplementary Fig. 1 were inadvertently …