Venous thrombosis

AS Wolberg, FR Rosendaal, JI Weitz, IH Jaffer… - Nature reviews Disease …, 2015 - nature.com
Venous thromboembolism (VTE) encompasses deep-vein thrombosis (DVT) and pulmonary
embolism. VTE is the leading cause of lost disability-adjusted life years and the third …

[HTML][HTML] The blood compatibility challenge. Part 1: Blood-contacting medical devices: The scope of the problem

IH Jaffer, JI Weitz - Acta biomaterialia, 2019 - Elsevier
Blood-contacting medical devices are an integral part of modern medicine. Such devices may
be used for only a few hours or may be implanted for life. Despite advances in biomaterial …

[HTML][HTML] An omniphobic lubricant-infused coating produced by chemical vapor deposition of hydrophobic organosilanes attenuates clotting on catheter surfaces

M Badv, IH Jaffer, JI Weitz, TF Didar - Scientific reports, 2017 - nature.com
Catheter associated thrombosis is an ongoing problem. Omniphobic coatings based on
tethering biocompatible liquid lubricants on self-assembled monolayers of hydrophobic …

Dabigatran is less effective than warfarin at attenuating mechanical heart valve‐induced thrombin generation

IH Jaffer, AR Stafford, JC Fredenburgh… - Journal of the …, 2015 - Am Heart Assoc
Background Patients with mechanical heart valves ( MHV ) require warfarin to prevent
thromboembolism. Although dabigatran was as effective as warfarin for stroke prevention in atrial …

Surgical ablation of atrial fibrillation: a systematic review and meta-analysis of randomized controlled trials

GR McClure, EP Belley-Cote, IH Jaffer, N Dvirnik… - EP …, 2018 - academic.oup.com
Aims The aim of this review was to assess the effect of concomitant surgical atrial fibrillation (AF)
ablation on postoperative freedom from AF and patient-important outcomes. Methods …

[HTML][HTML] Recent advances in the treatment of venous thromboembolism in the era of the direct oral anticoagulants

JI Weitz, IH Jaffer, JC Fredenburgh - F1000Research, 2017 - ncbi.nlm.nih.gov
The direct oral anticoagulants (DOACs) have now supplanted vitamin K antagonists (VKAs)
for the treatment of venous thromboembolism (VTE). The DOACs include dabigatran, which …

[HTML][HTML] Rivaroxaban and apixaban are less effective than enoxaparin for the prevention of catheter-induced clotting in vitro

…, RH Hussain, JC Fredenburgh, IH Jaffer… - Journal of Thrombosis …, 2023 - Elsevier
Background Central venous catheters are prone to clotting, particularly in patients with cancer.
Although low-molecular-weight heparin and direct oral anticoagulants, such as apixaban …

New-onset atrial fibrillation after transcatheter aortic valve replacement: a systematic review and meta-analysis

…, KJ Um, ME Vadakken, A Pandey, IH Jaffer… - Cardiovascular …, 2022 - jacc.org
Objectives The authors aimed to identify risk factors and outcomes associated with new-onset
atrial fibrillation (NOAF) after transcatheter aortic valve replacement (TAVR). Background …

Use of voice recognition software in an outpatient pediatric specialty practice

RM Issenman, IH Jaffer - Pediatrics, 2004 - publications.aap.org
Background. Voice recognition software (VRS), with specialized medical vocabulary, is being
promoted to enhance physician efficiency, decrease costs, and improve patient safety. This …

How did we get here?: a historical review and critical analysis of anticoagulation therapy following mechanical valve replacement

S MacIsaac, IH Jaffer, EP Belley-Côté, GR McClure… - Circulation, 2019 - Am Heart Assoc
Managing severe valvular heart disease with mechanical valve replacement necessitates
lifelong anticoagulation with a vitamin K antagonist. Optimal anticoagulation intensity for …