The synthesis, in vitro anti-HIV-1 activity, and decomposition pathwaysof several mono-nucleoside
phosphotriester derivativesof 3'-azido-2', 3'-dideoxythymidine (AZT) incorporating a …

On the basis of three different models (namely: ddU, AZT and PMEA), mononucleotide
phosphotriester derivatives were designed to be able to liberate the corresponding …

It was demonstrated that the use of neutral 2′,3′-dideoxyuridine phosphotriesters which
incorporate enzyme mediated bioreversible protection such as S-acetylthioethanol (SATE) or …

In this study, we developed a new method for the simultaneous determination of eight
endogenous ribonucleoside triphosphates and deoxyribonucleoside triphosphates based on a …

An analytical method coupling online solid-phase extraction (SPE) and liquid
chromatography–tandem mass spectrometry (LC-MS/MS) was developed to quantify 16 endogenous …

Despite the unquestionable therapeutic interest of bis(SATE) pronucleotides, a presystemic
metabolism preventing the delivery of the prodrugs in target cancer cells or tumours may …

Several studies have reported the possible growth of germanene on various metal surfaces.
However, the exact structure of the layers formed upon evaporation at or above room …

Two-dimensional Mott materials have recently been reported in the dichalcogenide family
with high potential for Mottronic applications. Nevertheless, their widespread use as a single …

Unlike silicene, for which the demonstration of its existence has been done through numerous
independent studies, the possibility of growing epitaxial germanene remains highly …

Two-dimensional honeycomb lattices beyond graphene, such as germanene, promise new
physical properties such as quantum spin Hall effect. While there have been many claims of …