[HTML][HTML] Human glia can both induce and rescue aspects of disease phenotype in Huntington disease

…, X Li, D Chandler-Militello, J Mauceri… - Nature …, 2016 - nature.com
The causal contribution of glial pathology to Huntington disease (HD) has not been heavily
explored. To define the contribution of glia to HD, we established human HD glial chimeras …

Elevated soluble c-erbB-2 antigen levels in the serum and effusions of a proportion of breast cancer patients.

K Leitzel, Y Teramoto, E Sampson, J Mauceri… - Journal of clinical …, 1992 - ascopubs.org
PURPOSE An enzyme-linked immunosorbent assay (ELISA) for the extracellular domain of
the c-erbB-2 oncogene product was developed and evaluated to determine if soluble c-erbB-…

Measuring radiant emissions from entire prescribed fires with ground, airborne and satellite sensors–RxCADRE 2012

…, A Gerace, D Peterson, J Mauceri - … Journal of Wildland …, 2015 - CSIRO Publishing
Characterising radiation from wildland fires is an important focus of fire science because
radiation relates directly to the combustion process and can be measured across a wide range …

Blockade of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation

…, MA Beckett, NT Jaskowiak, DP Calvin, HJ Mauceri… - Cancer research, 1999 - AACR
The family of vascular endothelial growth factor (VEGF) proteins include potent and specific
mitogens for vascular endothelial cells that function in the regulation of angiogenesis. …

Combined effects of angiostatin and ionizing radiation in antitumour therapy

HJ Mauceri, NN Hanna, MA Beckett, DH Gorski… - Nature, 1998 - nature.com
Angiogenesis, the formation of new capillaries from pre-existing vessels, is essential for tumour
progression 1 , 2 , 3 , 4 , 5 . Angiostatin, a proteolytic fragment of plasminogen 6 that was …

Radiation-induced tumour necrosis factor-α expression: clinical application of transcriptional and physical targeting of gene therapy

…, CR King, PH Fischer, HJ Mauceri - The Lancet …, 2002 - thelancet.com
Promising data are emerging on a new anticancer agent, Ad. EGR-TNF, an adenoviral
vector, which contains radio-inducible DNA sequences from the early growth response (EGR1) …

Spatial and temporal control of gene therapy using ionizing radiation

DE Hallahan, HJ Mauceri, LP Seung, EJ Dunphy… - Nature medicine, 1995 - nature.com
Activation of transcription of the Egr-1 gene by X-rays is regulated by the promoter region of
this gene. We linked the radiation-inducible promoter region of the Egr-1 gene to the gene …

Tumour-endothelium interactions in co-culture: coordinated changes of gene expression profiles and phenotypic properties of endothelial cells

…, T Darga, CK Brown, HJ Mauceri… - Journal of cell …, 2003 - journals.biologists.com
Tumour angiogenesis is a complex process based upon a sequence of interactions between
tumour cells and endothelial cells. To model tumour/endothelial-cell interactions, we co-…

In Vitro and in Vivo Activity of Protein Kinase C Inhibitor Chelerythrine Chloride Induces Tumor Cell Toxicity and Growth Delay in Vivo

SJ Chmura, ME Dolan, A Cha, HJ Mauceri… - Clinical Cancer …, 2000 - AACR
Although clonogenic or divisional death is the main mechanism by which DNA-damaging
agents demonstrate antitumor activity, recent data indicate that strategies specifically designed …

Blockade of tumor necrosis factor α signaling in tumor-associated macrophages as a radiosensitizing strategy

Y Meng, MA Beckett, H Liang, HJ Mauceri… - Cancer research, 2010 - AACR
Most cancer patients receive radiotherapy during the course of their disease. Improvements
in the therapeutic index have been based mainly on physical improvements in delivery, as …