As a group, cartilage tumours are the most common primary bone lesions. They range from
benign lesions, such as enchondromas and osteochondromas, to malignant chondrosarcoma…

Sarcomas are mesenchymal cancers, which, in many cases, have distinctive molecular
features. Limb-sparing surgery delivered at specialised sarcoma centres as part of a …

… J Wunder and A Davis provided the prognostic variables used to describe the study sample,
and, with R Bell and B O'Sullivan, developed the wound complication assessment criteria. C …

BACKGROUND AND PURPOSE: This study compared late radiation morbidity in patients
with extremity soft tissue sarcoma randomized to treatment by pre- (50Gy) or postoperative (…

PURPOSE More than 90% of Ewing's sarcomas (ES) contain a fusion of the EWS and FLI1
genes, due to the t(11;22)(q24;q12) translocation. At the molecular level, the EWS-FLI1 …

A multicentric retrospective study of giant cell tumor of bone was conducted among Canadian
surgeons. The hypothesis was that no differences would be found in health status, function…

Purpose: To retrospectively analyze the long term results of treatment and the patterns of
failure for patients with chordoma of the sacrum, base of skull and mobile spine treated …

Several types of pediatric cancers reportedly contain high-frequency missense mutations in
histone H3, yet the underlying oncogenic mechanism remains poorly characterized. Here we …

Background The current American Joint Committee on Cancer/Union for International Cancer
Control (AJCC/UICC) staging system does not have sufficient details to encompass the …

Aggressive fibromatosis (also called desmoid tumor) occurs as a sporadic lesion or as part
of Familial Adenomatous Polyposis, which is caused by germ line mutations in the …