Photolyzed rhodopsin catalyzes the exchange of GTP for FDP bound to a protein in retinal
rod outer segments. We previously proposed that the GTP complex of this protein regulates …

Primate cones maximally sensitive to short wavelength light (blue cones) have been
previously identified by using indirect methods. We stained 7 wholemounted human retinas …

Color vision is facilitated by distinct populations of cone photoreceptors in the retina. In rodents,
cones expressing different opsin photopigments are sensitive to middle (M,'green') and …

Vertebrate retinal photoreceptors recover from photoexcitation-induced hydrolysis of guanosine
3′, 5′-monophosphate (cyclic GMP) by resynthesizing cyclic GMP, which reopens …

Optokinetic and phototactic behaviors of zebrafish larvae were examined for their usefulness
in screening for recessive defects in the visual system. The optokinetic response can be …

Retinal transducin, a guanine nucleotide regulatory protein (referred to as a G protein) that
activates a cGMP phosphodiesterase in photoreceptor cells, is comprised of three subunits. …

Phosphorylation is thought to be an essential first step in the prompt deactivation of photoexcited
rhodopsin. In vitro, the phosphorylation can be catalyzed either by rhodopsin kinase (…

Recoverin (Rv) is a myristoylated Ca 2+ -binding protein present primarily in bovine
photoreceptors. It represents a newly identified family of neuronal specific Ca 2+ -binding proteins …

The guanosine triphosphate-binding proteins (G proteins) found in a variety of tissues
transduce signals generated by ligand binding to cell surface receptors into changes in …

A human photoreceptor membrane guanylyl cyclase, RetGC, was recently cloned and
expressed, but its localization and manner of regulation were not defined. We report here that …