User profiles for James Brophy
james m brophyProfessor of Medicine and Epidemiology and Biostatistics, McGill University Verified email at mcgill.ca Cited by 29493 |
A hierarchical Bayesian meta-analysis of randomised clinical trials of drug-eluting stents
MN Babapulle, L Joseph, P Bélisle, JM Brophy… - The Lancet, 2004 - thelancet.com
Background Drug-eluting stents (DES) are associated with lower restenosis rates than bare-metal
stents (BMS), but the benefits and safety of the new devices have not been …
stents (BMS), but the benefits and safety of the new devices have not been …
β-Blockers in congestive heart failure: a Bayesian meta-analysis
JM Brophy, L Joseph, JL Rouleau - Annals of internal medicine, 2001 - acpjournals.org
Purpose: Congestive heart failure is an important cause of patient morbidity and mortality.
Although several randomized clinical trials have compared β-blockers with placebo for …
Although several randomized clinical trials have compared β-blockers with placebo for …
Assaulted and unheard: violence against healthcare staff
JT Brophy, MM Keith, M Hurley - New solutions: a journal of …, 2018 - journals.sagepub.com
Healthcare workers regularly face the risk of violent physical, sexual, and verbal assault
from their patients. To explore this phenomenon, a collaborative descriptive qualitative study …
from their patients. To explore this phenomenon, a collaborative descriptive qualitative study …
Risk of acute myocardial infarction with NSAIDs in real world use: bayesian meta-analysis of individual patient data
…, L Nadeau, A Helin-Salmivaara, E Garbe, JM Brophy - bmj, 2017 - bmj.com
Objective To characterise the determinants, time course, and risks of acute myocardial
infarction associated with use of oral non-steroidal anti-inflammatory drugs (NSAIDs). Design …
infarction associated with use of oral non-steroidal anti-inflammatory drugs (NSAIDs). Design …
Reduction of morbidity and mortality by statins, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers in patients with chronic obstructive …
…, LE Levesque, JM FitzGerald, JM Brophy - Journal of the American …, 2006 - jacc.org
Objectives : The purpose of this study was to determine if statins (hydroxymethylglutaryl
CoA reductase inhibitors [HMG-CoA]), angiotensin-converting enzyme (ACE) inhibitors, and …
CoA reductase inhibitors [HMG-CoA]), angiotensin-converting enzyme (ACE) inhibitors, and …
Should meta-analyses of interventions include observational studies in addition to randomized controlled trials? A critical examination of underlying principles
Some authors argue that systematic reviews and meta-analyses of intervention studies
should include only randomized controlled trials because the randomized controlled trial is a …
should include only randomized controlled trials because the randomized controlled trial is a …
Drug–drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding
Background: Anticoagulants and antiplatelet drugs (eg, warfarin, clopidogrel and acetylsalicylic
acid) are key therapeutic agents in the treatment of cardiovascular diseases. However, …
acid) are key therapeutic agents in the treatment of cardiovascular diseases. However, …
Association of selective and conventional nonsteroidal antiinflammatory drugs with acute renal failure: a population-based, nested case-control analysis
…, B Zhang, T Hutchinson, JM Brophy - American Journal of …, 2006 - academic.oup.com
Conventional nonsteroidal antiinflammatory drugs (NSAIDs) are associated with acute renal
failure, but cyclooxygenase-2 inhibitors have not been comparatively evaluated. The …
failure, but cyclooxygenase-2 inhibitors have not been comparatively evaluated. The …
Association between timeliness of reperfusion therapy and clinical outcomes in ST-elevation myocardial infarction
Context Guidelines emphasize the importance of rapid reperfusion of patients with ST-elevation
myocardial infarction (STEMI) and specify a maximum delay of 30 minutes for fibrinolysis …
myocardial infarction (STEMI) and specify a maximum delay of 30 minutes for fibrinolysis …
Evidence for use of coronary stents: a hierarchical bayesian meta-analysis
JM Brophy, P Belisle, L Joseph - Annals of internal medicine, 2003 - acpjournals.org
Background: Coronary stents are widely used in interventional cardiology, but a current
quantitative systematic overview comparing routine coronary stenting with standard …
quantitative systematic overview comparing routine coronary stenting with standard …