Human pancreatic islet in vitro culture is very challenging and requires the presence of
various extra cellular matrix (ECM) components in a three-dimensional environment, which …

Both type 2 diabetes (T2D) and obesity are characterized by excessive hyperlipidaemia and
subsequent lipid droplet (LD) accumulation in adipose tissue. To investigate whether LDs …

2-Aminopurine (2AP), a base analog, causes both transition and frameshift mutations in
Escherichia coli. The analog is thought to cause mutations by two mechanisms: directly, by …

Objective To compare quality-of-care indicators for management of patients with chronic kidney
disease (CKD) and type 2 diabetes among the James Bay Cree of Northern Quebec with …

Expediting life-saving care for hemorrhagic shock through multi-disciplinary code protocols
is a potential method to improve outcomes. Trauma codes have become standard of care at …

Objective The objective of this study was to compare hemodynamic stability, times to
assessment and intervention, and mortality outcomes between trauma code and ruptured aortic …

Objectives The objective of this study was to evaluate the outcomes, usefulness, and cost-effectiveness
of routine pathological examination of vascular surgery specimens. Methods All …

Diabetes is characterized by a complete (type 1) or partial (type 2) loss of pancreatic beta
cells. Regeneration of beta-cell mass is an important goal of diabetes research. Development …

Objective The objective of this study was to analyze long-term results of popliteal artery
aneurysm repair through a posterior approach. Methods We performed a retrospective analysis …

This project could not have been possible without the generous financial support provided
by the Canadian Patient Safety Institute and the matching support provided by the Research …