User profiles for Jay Wunder

jay s wunder

sinai health system, university of toronto, canada
Verified email at sinaihealth.ca
Cited by 25749

Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial

…, R Turcotte, R Bell, C Catton, P Chabot, J Wunder… - The Lancet, 2002 - thelancet.com
Background External-beam radiotherapy (delivered either preoperatively or postoperatively)
is frequently used in local management of sarcomas in the soft tissue of limbs, but the two …

Late radiation morbidity following randomization to preoperative versus postoperative radiotherapy in extremity soft tissue sarcoma

…, R Bell, C Catton, P Chabot, J Wunder… - Radiotherapy and …, 2005 - Elsevier
BACKGROUND AND PURPOSE: This study compared late radiation morbidity in patients
with extremity soft tissue sarcoma randomized to treatment by pre- (50Gy) or postoperative (…

EWS-FLI1 fusion transcript structure is an independent determinant of prognosis in Ewing's sarcoma.

…, J Ginsberg, R Womer, ER Lawlor, J Wunder… - Journal of Clinical …, 1998 - ascopubs.org
PURPOSE More than 90% of Ewing's sarcomas (ES) contain a fusion of the EWS and FLI1
genes, due to the t(11;22)(q24;q12) translocation. At the molecular level, the EWS-FLI1 …

Giant cell tumor of long bone: a Canadian Sarcoma Group study

RE Turcotte, JS Wunder, MH Isler, RS Bell… - Clinical Orthopaedics …, 2002 - journals.lww.com
A multicentric retrospective study of giant cell tumor of bone was conducted among Canadian
surgeons. The hypothesis was that no differences would be found in health status, function…

Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape

…, S Venneti, M Hameed, BR Pawel, JS Wunder… - Science, 2016 - science.org
Several types of pediatric cancers reportedly contain high-frequency missense mutations in
histone H3, yet the underlying oncogenic mechanism remains poorly characterized. Here we …

Chordoma: long-term follow-up after radical photon irradiation

…, B Cummings, V Fornasier, J Wunder - Radiotherapy and …, 1996 - Elsevier
Purpose: To retrospectively analyze the long term results of treatment and the patterns of
failure for patients with chordoma of the sacrum, base of skull and mobile spine treated …

Development and external validation of two nomograms to predict overall survival and occurrence of distant metastases in adults after surgical resection of localised …

…, AP Dei Tos, HG Smith, L Mariani, JS Wunder… - The Lancet …, 2016 - thelancet.com
Background The current American Joint Committee on Cancer/Union for International Cancer
Control (AJCC/UICC) staging system does not have sufficient details to encompass the …

Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor)

S Tejpar, F Nollet, C Li, JS Wunder, G Michils… - Oncogene, 1999 - nature.com
Aggressive fibromatosis (also called desmoid tumor) occurs as a sporadic lesion or as part
of Familial Adenomatous Polyposis, which is caused by germ line mutations in the …

Residual disease following unplanned excision of a soft-tissue sarcoma of an extremity

…, R Kandel, J Levesque, B O'SULLIVAN, JAY Wunder… - JBJS, 1996 - journals.lww.com
Sixty-five patients who had been referred to our unit for additional management after an
unplanned excision of a soft-tissue sarcoma of an extremity at another institution were studied …

Cartilage tumours and bone development: molecular pathology and possible therapeutic targets

JVMG Bovée, PCW Hogendoorn, JS Wunder… - Nature Reviews …, 2010 - nature.com
As a group, cartilage tumours are the most common primary bone lesions. They range from
benign lesions, such as enchondromas and osteochondromas, to malignant chondrosarcoma…