Transfer of sufficient IgG to the newborn calf via colostrum is vital to provide it with adequate
immunological protection and resistance to disease. The objectives of the present study …

The first family identified as having a nonsyndromic intellectual disability was mapped in
1988. Here we show that a mutation of IQSEC2, encoding a guanine nucleotide exchange …

Dynamic regulation of the localization and function of NMDA receptors (NMDARs) is critical
for synaptic development and function. The composition and localization of NMDAR subunits …

The NMDA-type glutamate receptor (NMDAR) is essential for synaptogenesis, synaptic
plasticity, and higher cognitive function. Emerging evidence indicates that NMDAR Ca 2+ …

HER2 mutations are infrequent genomic events in biliary tract cancers (BTCs). Neratinib, an
irreversible, pan-HER, oral tyrosine kinase inhibitor, interferes with constitutive receptor …

NMDARs (N-methyl-D-aspartate receptors) are critical for synaptic function throughout the
CNS (central nervous system). NMDAR-mediated Ca 2+ influx is implicated in neuronal …

Colonic migrating motor complexes (CMMCs) are spontaneous, anally propagating
constrictions, repeating every 3–5 min in mouse colon in vitro. They are regulated by the enteric …

Cancer cachexia is a common, debilitating condition with limited therapeutic options. Using
an established mouse model of lung cancer, we find that cachexia is characterized by …

Background Patients with head and neck cancer experience complex posttreatment challenges.
In a preliminary uncontrolled study, we evaluated the extent to which they can benefit …

Human immunodeficiency virus (HIV)–infected patients are at increased risk for
development of pulmonary complications, including chronic obstructive pulmonary disease (COPD). …