Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1–2 trials
Background Entrectinib is a potent inhibitor of tropomyosin receptor kinase (TRK) A, B, and
C, which has been shown to have anti-tumour activity against NTRK gene fusion-positive …
C, which has been shown to have anti-tumour activity against NTRK gene fusion-positive …
[BOOK][B] Natural attenuation of fuels and chlorinated solvents in the subsurface
The first comprehensive guide to one of today's most innovative approaches to environmental
contamination Natural attenuation is gaining increasing attention as a nonintrusive, cost-…
contamination Natural attenuation is gaining increasing attention as a nonintrusive, cost-…
Microbial ecology of the terrestrial subsurface
WC Ghiorse, JT Wilson - Advances in applied microbiology, 1988 - Elsevier
Publisher Summary This chapter presents a current view of the microbial ecology of the
terrestrial subsurface by considering the ecology of shallow aquifer sediments. The properties of …
terrestrial subsurface by considering the ecology of shallow aquifer sediments. The properties of …
[PDF][PDF] Biotransformation of trichloroethylene in soil
JT Wilson, BH Wilson - Applied and Environmental Microbiology, 1985 - Am Soc Microbiol
… WILSON'* AND BARBARA H. WILSON2 Robert S. Kerr Environmental Research Laboratory,
Ada, Oklahoma 74820,1 and Environmental and Ground Water Institute, The University …
Ada, Oklahoma 74820,1 and Environmental and Ground Water Institute, The University …
Equivalence of microbial biomass measures based on membrane lipid and cell wall components, adenosine triphosphate, and direct counts in subsurface aquifer …
DL Balkwill, FR Leach, JT Wilson, JF McNabb… - Microbial Ecology, 1988 - Springer
An uncontaminated subsurface aquifer sediment contains a sparse microbial community
consisting primarily of coccobacillary bacteria of relatively uniform size which can be counted …
consisting primarily of coccobacillary bacteria of relatively uniform size which can be counted …
Endosomolytic polymersomes increase the activity of cyclic dinucleotide STING agonists to enhance cancer immunotherapy
Cyclic dinucleotide (CDN) agonists of stimulator of interferon genes (STING) are a
promising class of immunotherapeutics that activate innate immunity to increase tumour …
promising class of immunotherapeutics that activate innate immunity to increase tumour …
Chemical and biomolecular strategies for STING pathway activation in cancer immunotherapy
KM Garland, TL Sheehy, JT Wilson - Chemical reviews, 2022 - ACS Publications
The stimulator of interferon genes (STING) cellular signaling pathway is a promising target for
cancer immunotherapy. Activation of the intracellular STING protein triggers the production …
cancer immunotherapy. Activation of the intracellular STING protein triggers the production …
Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1–2 trials
…, T Seto, BC Cho, MR Patel, CH Chiu, T John… - The Lancet …, 2020 - thelancet.com
Background Recurrent gene fusions, such as ROS1 fusions, are oncogenic drivers of various
cancers, including non-small-cell lung cancer (NSCLC). Up to 36% of patients with ROS1 …
cancers, including non-small-cell lung cancer (NSCLC). Up to 36% of patients with ROS1 …
[PDF][PDF] Technical protocol for evaluating natural attenuation of chlorinated solvents in ground water
…, EK Gordon, JT Wilson, BH Wilson… - Cincinnati, Ohio, USA …, 1998 - researchgate.net
Over the past several years remediation by natural attenuation has become increasingly
accepted as a remedial alternative for organic compounds dissolved in groundwater. The …
accepted as a remedial alternative for organic compounds dissolved in groundwater. The …
pH-Responsive nanoparticle vaccines for dual-delivery of antigens and immunostimulatory oligonucleotides
Protein subunit vaccines offer important potential advantages over live vaccine vectors but
generally elicit weaker and shorter-lived cellular immune responses. Here we investigate the …
generally elicit weaker and shorter-lived cellular immune responses. Here we investigate the …