Administration of denosumab preserves bone mineral density at the knee in persons with subacute spinal cord injury: findings from a randomized clinical trial

…, L Hao, IA McClure, JC Hobson… - Journal of Bone and …, 2020 - academic.oup.com
Persons with neurologically motor complete spinal cord injury (SCI) have a marked loss of
bone mineral density (BMD) of the long bones of the lower extremities, predisposing them to …

ETB receptor-mediated vasodilation is regulated by estradiol in young women

…, SJ McGinty, LM Welti, JC Hobson… - American Journal …, 2021 - journals.physiology.org
The endothelin-B (ET B ) receptor is a key regulator of vascular endothelial function in women.
We have previously shown that the ET B receptor mediates vasodilation in young women, …

Blood lipid markers are associated with hippocampal viscoelastic properties and memory in humans

…, LV Hiscox, TM DeConne, JC Hobson… - Journal of Cerebral …, 2021 - journals.sagepub.com
Age-related memory loss shares similar risk factors as cardiometabolic diseases including
elevated serum triglycerides (TGs) and low-density lipoprotein cholesterol (LDL-C) and …

Altered endothelial ETB receptor expression in postmenopausal women

…, LN Shoemaker, JC Hobson… - American Journal …, 2020 - journals.physiology.org
The endothelin system plays an important role in mediating vascular function. The endothelin-B
receptor (ET B R) on endothelial cells mediates vasodilation via nitric oxide production. …

Establishing a threshold to predict risk of cardiovascular disease from the serum triglyceride and high-density lipoprotein concentrations in persons with spinal cord …

MF La Fountaine, CM Cirnigliaro, JC Hobson… - Spinal Cord, 2018 - nature.com
Study design Retrospective cohort. Objective This report identified the serum triglyceride (TG)
concentrations in persons with spinal cord injury (SCI) and able-bodied (AB) individuals …

Progressive sublesional bone loss extends into the second decade after spinal cord injury

…, MJ Myslinski, P Asselin, JC Hobson… - Journal of Clinical …, 2019 - Elsevier
Objective: The rate of areal bone mineral density (aBMD) loss at the knee (distal femur (DF)
and proximal tibia ) and hip (femoral neck (FN) and total hip (TH)) was determined in …

Biomarkers of inflammation in persons with chronic tetraplegia

…, M LaFountaine, N Kahn, J Hobson… - Journal of breath …, 2015 - iopscience.iop.org
In addition to lung volume restriction, individuals with chronic tetraplegia exhibit reduced
airway caliber and bronchodilator responsiveness similar to persons with asthma. In asthma, …

Bronchodilator effects of ipratropium bromide and albuterol sulfate among subjects with tetraplegia

GJ Schilero, JC Hobson, K Singh… - The Journal of Spinal …, 2018 - Taylor & Francis
Objective: In addition to lung volume restriction, persons with chronic tetraplegia demonstrate
obstructive airway physiology evinced by pharmacologically-induced bronchodilation. We …

Cardiometabolic risk factors are associated with immune cell mitochondrial respiration in humans

…, ER Muñoz, F Sanjana, JC Hobson… - American Journal …, 2020 - journals.physiology.org
Modifiable cardiometabolic risk factors induce the release of proinflammatory cytokines and
reactive oxygen species from circulating peripheral blood mononuclear cells (PBMCs), …

Predicting cardiometabolic risk from visceral abdominal adiposity in persons with chronic spinal cord injury

CM Cirnigliaro, MF La Fountaine, JC Hobson… - Journal of Clinical …, 2021 - Elsevier
Persons with spinal cord injury (SCI) have increased adiposity that may predispose to
cardiovascular disease compared to those who are able-bodied (AB). The purpose of this study …