We determined the extent to which additional binding energy could be achieved by diversifying
the complementarity determining regions (CDRs) located in the center of the antibody …

The hyaluronan in normal synovial fluid plays an important role in joint homeostasis. It
contributes to joint lubrication, buffers load transmission across articular surfaces, provides a …

Patients with late-stage Kellgren-Lawrence knee osteoarthritis received a single intra-articular
injection of 1, 10, or 50 million bone marrow mesenchymal stromal cells (BM-MSCs) in a …

Colorectal cancer (CRC) is often curable and preventable using current screening modalities.
Unfortunately, screening compliance remains low, partly due to patient dissatisfaction with …

Purpose: We applied a unique method to identify genes expressed in whole blood that can
serve as biomarkers to detect colorectal cancer (CRC). Experimental Design: Total RNA was …

Background/Purpose: Regression of a cystic adenomatoid malformation (CAM) in a fetus is
well described. Little, however, is known about the postnatal course of these infants. This …

Purpose: Recent data indicate that cDNA microarray gene expression profile of blood cells
can reflect disease states and thus have diagnostic value. We tested the hypothesis that …

Background Chronic, low-grade inflammation of the synovium (synovitis) is a hallmark of
osteoarthritis (OA), thus understanding of OA immunobiology, mediated by immune effectors, is …

… The three BK analogues were assayed on isolated rat uterus by the protocol described
by Marshall et al.18 for angiotensin II and in binding assays to bovine brain membranes as …

OBJECTIVE. This study was designed to assess the effect of prenatal sonographic diagnosis
on the treatment of congenital cystic adenomatoid malformation of the lung. MATERIALS …