OBJECT The objective of this study was to determine the clinical comparative effectiveness
and adverse event rates of posterior minimally invasive surgery (MIS) compared with open …

Background Although minimally invasive surgical (MIS) approaches to the lumbar spine for
posterior fusion are increasingly being utilized, the comparative outcomes of MIS and open …

… This article is a substantial revised version of Kala Sundararajan's thesis submitted to the
University of Western Ontario. Funding for this research by the Canadian Institutes of Health …

Osteoarthritis (OA) of spine (facet joints [FJs]) is one of the major causes of severe low back
pain and disability worldwide. The degeneration of facet cartilage is a hallmark of FJ OA. …

Multiple factors can help predict knee osteoarthritis (OA) patients from healthy individuals,
including age, sex, and BMI, and possibly metabolite levels. Using plasma from individuals …

Introduction Diversion of prescription opioid medication is a contributor to the opioid epidemic.
Safe handling practices can reduce the risk of diversion. We aimed to understand: 1) if …

Background The incremental hospital cost and length of stay (LOS) associated with adverse
events (AEs) has not been well characterized for planned and unplanned inpatient spine, …

Background Interest in postoperative healthcare utilization has increased following the
implementation of episode-of-care funding for elective orthopedic surgery. Most efforts have …

Objective To examine patterns of depressive symptoms before and over the year following
osteoarthritis ( OA ) surgery, stratified by joint and postsurgical outcome. Methods Participants …

Background. In an attempt to correlate biomarkers with disease, serum-based biomarkers
often are compared between individuals with osteoarthritis (OA) and control subjects. However…