This study demonstrates that SLC7A11 in PDAC stromal cells is important for the tumor-promoting
activity of CAFs and validates a clinically translatable nanomedicine for therapeutic …

The provision of acute surgical care in the public sector is becoming increasingly difficult
because of limitation of resources and the unpredictability of access to theatres during the …

Simple Summary While survival rates for many cancers have improved dramatically over the
last 20 years, patients with pancreatic cancer have persistently poor outcomes. The majority …

OBJECTIVE: We sought to evaluate the effect of radiofrequency ablation (RFA) on pulmonary
vessels with respect to potential of injury of these structures, to assess perfusion-mediated “…

The poor prognosis of pancreatic ductal adenocarcinoma (PDAC) is attributed to the highly
fibrotic stroma and complex multi-cellular microenvironment that is difficult to fully recapitulate …

Background: Microvascular free‐tissue transfer is now the primary method of reconstruction
in many centres. The aim of this study was to evaluate the applications, complications and …

Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest of all
major cancers. We now know that a ‘one-size-fits-all’ approach when treating PDAC patients …

BACKGROUND: Intraoperative blood loss has been shown to be an important factor
correlating with morbidity and mortality in liver surgery. A 5-cm long instrument with variably …

Presents the case of a 70-year-old man with diverticular disease. Clinical manifestations of
the disease; Findings of a computed tomography scan of the patient's abdomen; Description …

Background While combination therapy with nab-paclitaxel/gemcitabine (nab-gem) is effective
in pancreatic ductal adenocarcinoma (PDAC), its efficacy as perioperative chemotherapy …