Latest developments in molecular tracers for fluorescence image-guided cancer surgery

S Hernot, L van Manen, P Debie, JSD Mieog… - The lancet …, 2019 - thelancet.com
Real-time intraoperative guidance is essential during oncological surgery for complete and
safe tumour resection. Fluorescence imaging in the near-infrared spectrum has shown …

A practical guide for the use of indocyanine green and methylene blue in fluorescence‐guided abdominal surgery

L van Manen, HJM Handgraaf, M Diana… - Journal of surgical …, 2018 - Wiley Online Library
Near‐infrared (NIR) fluorescence imaging is gaining clinical acceptance over the last years
and has been used for detection of lymph nodes, several tumor types, vital structures and …

[HTML][HTML] The clinical usefulness of optical coherence tomography during cancer interventions

L van Manen, J Dijkstra, C Boccara, E Benoit… - Journal of cancer …, 2018 - Springer
Introduction Tumor detection and visualization plays a key role in the clinical workflow of a
patient with suspected cancer, both in the diagnosis and treatment. Several optical imaging …

Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer

…, A De Luca, N Chun, G Suriano, S Zaor, L Van Manen… - Jama, 2007 - jamanetwork.com
ContextHereditary diffuse gastric cancer is caused by germline mutations in the epithelial
cadherin (CDH1) gene and is characterized by an increased risk for diffuse gastric cancer and …

Elevated CEA and CA19-9 serum levels independently predict advanced pancreatic cancer at diagnosis

L van Manen, JV Groen, H Putter, AL Vahrmeijer… - Biomarkers, 2020 - Taylor & Francis
Purpose: It is suggested that tumour markers carcinoembryonic antigen (CEA) and carbohydrate
antigen 19-9 (CA19-9) could be used to predict the stage of pancreatic cancer. However…

[HTML][HTML] A systematic review of the use of near-infrared fluorescence imaging in patients with peripheral artery disease

P van den Hoven, S Ooms, L van Manen… - Journal of Vascular …, 2019 - Elsevier
Objective In the diagnosis of peripheral artery disease (PAD), the ankle-brachial index plays
an important role. However, results of the ankle-brachial index are unreliable in patients …

[HTML][HTML] Stage-specific value of carbohydrate antigen 19-9 and carcinoembryonic antigen serum levels on survival and recurrence in pancreatic cancer: a single …

L van Manen, JV Groen, H Putter, M Pichler… - Cancers, 2020 - mdpi.com
Simple Summary Pancreatic cancer is one of the most aggressive cancers with a poor
survival. Only the minority of patients can be treated by extensive surgery, which is associated …

[HTML][HTML] Validation of full-field optical coherence tomography in distinguishing malignant and benign tissue in resected pancreatic cancer specimens

L Van Manen, PL Stegehuis, A Farina-Sarasqueta… - PLoS …, 2017 - journals.plos.org
Background Pancreatic cancer is the fourth leading cause of cancer-related mortality in the
United States. The minority of patients can undergo curative-intended surgical therapy due to …

Diagnostic, therapeutic and economic consequences of a positive urinary antigen test for Legionella spp. in patients admitted with community-acquired pneumonia: a …

MF Engel, L Van Manen, AIM Hoepelman… - Journal of Clinical …, 2013 - jcp.bmj.com
Aims A positive urinary antigen test for Legionella spp. (Legionella urinary antigen test; LUAT)
allows an early switch from empiric to targeted treatment (TT) in hospitalised, community-…

A decision aid for men with early stage prostate cancer: theoretical basis and a test by surrogate patients

…, MD Brundage, L Van Manen - Health …, 2001 - Wiley Online Library
Background We developed a decision aid for patients with curable prostate cancer based
on Svenson’s DiffCon Theory of Decision Making. This study was designed to determine if …