User profiles for L.A. MacLaren
Leslie MacLarenProfessor, Animal Physiology, Dalhousie University Verified email at dal.ca Cited by 1710 |
Effect of interferon-τ on prostaglandin biosynthesis, transport, and signaling at the time of maternal recognition of pregnancy in cattle: evidence of polycrine actions of …
…, S Kimmins, P Chapdelaine, LA Maclaren… - …, 2004 - academic.oup.com
Recognition and establishment of pregnancy involve several molecular and cellular interactions
among the conceptus, uterus, and corpus luteum (CL). In ruminants, interferon-τ (IFNτ) …
among the conceptus, uterus, and corpus luteum (CL). In ruminants, interferon-τ (IFNτ) …
Oestrous cycle and pregnancy effects on the distribution of oestrogen and progesterone receptors in bovine endometrium
S Kimmins, LA MacLaren - Placenta, 2001 - Elsevier
Reproductive cyclicity and pregnancy require cell and tissue specific expression of oestrogen
(OR) and progesterone receptors (PR). To determine the effects of cycle day and early …
(OR) and progesterone receptors (PR). To determine the effects of cycle day and early …
Implantation-associated changes in bovine uterine expression of integrins and extracellular matrix
…, S Kimmins, JA Small, LA MacLaren - Biology of …, 2002 - academic.oup.com
Appropriate integrin expression appears to be necessary for successful implantation of human
embryos and varies considerably among species. The present study was undertaken to …
embryos and varies considerably among species. The present study was undertaken to …
Derivation and validation of the Denver Human Immunodeficiency Virus (HIV) risk score for targeted HIV screening
…, RE Rothman, YH Hsieh, LA MacLaren… - American journal of …, 2012 - academic.oup.com
Targeted screening remains an important approach to human immunodeficiency virus (HIV)
testing. The authors aimed to derive and validate an instrument to accurately identify …
testing. The authors aimed to derive and validate an instrument to accurately identify …
Molecular Cloning and Characterization of Bovine Prostaglandin E2 Receptors EP2 and EP4: Expression and Regulation in Endometrium and Myometrium during …
…, P Chapdelaine, V Emond, JJ Kim, LA MacLaren… - …, 2003 - academic.oup.com
Prostaglandins (PGs) play important functions in the reproductive system, and PGE 2 appears
necessary for recognition of pregnancy. We have found that PGE 2 is able to increase …
necessary for recognition of pregnancy. We have found that PGE 2 is able to increase …
Expression of cyclooxygenase-2 and granulocyte-macrophage colony-stimulating factor in the endometrial epithelium of the cow is up-regulated during early …
V Emond, LA MacLaren, S Kimmins… - Biology of …, 2004 - academic.oup.com
On the basis of results obtained in vitro, we previously proposed a model in which signals
from the conceptus, namely interferon-tau (IFN-τ) and prostaglandin E 2 , increase the …
from the conceptus, namely interferon-tau (IFN-τ) and prostaglandin E 2 , increase the …
Peroxisome proliferator-activated receptor (PPAR) expression in cultured bovine endometrial cells and response to omega-3 fatty acid, growth hormone and agonist …
The peroxisome proliferator-activated receptors (PPARs) are a family of nuclear transcription
factors thought to act as receptors for polyunsaturated fatty acids and to reduce production …
factors thought to act as receptors for polyunsaturated fatty acids and to reduce production …
[HTML][HTML] Pregnancy, bovine somatotropin, and dietary n-3 fatty acids in lactating dairy cows: II. Endometrial gene expression related to maintenance of pregnancy
The objectives were to examine the effects of bovine somatotropin (bST), pregnancy, and
dietary fatty acids on expression of key endometrial genes and proteins regulating …
dietary fatty acids on expression of key endometrial genes and proteins regulating …
[HTML][HTML] Effects of dietary inclusion of seaweed, heat stress and genetic strain on performance, plasma biochemical and hematological parameters in laying hens
…, BM Rathgeber, CM Stupart, J MacIsaac, LA MacLaren - Animals, 2020 - mdpi.com
Simple Summary Prebiotics such as seaweeds have been proposed as positive influencers
on hen health and productivity, including their response to stressors such as heat. The …
on hen health and productivity, including their response to stressors such as heat. The …
Estrogen selectively up-regulates the phospholipid hydroperoxide glutathione peroxidase in the oviducts
J Lapointe, S Kimmins, LA MacLaren… - Endocrinology, 2005 - academic.oup.com
The oviduct plays a crucial role in mammalian reproduction by providing an optimal
environment for the final maturation and transport of gametes, fertilization, and early embryonic …
environment for the final maturation and transport of gametes, fertilization, and early embryonic …