Type I interferons (IFN-Is) are emerging as key drivers of inflammation and immunosuppression
in chronic infection. Control of these infections requires IFN-I signaling; however, …

To support the development of new techniques and technology in facial aesthetics, sophisticated
ways of measuring outcomes are needed. The objective of this study was to develop …

Type I and II interferons (IFNs) stimulate pro-inflammatory programs that are critical for immune
activation, but also induce immune-suppressive feedback circuits that impede control of …

Purpose To assess cardiovascular risk factors (CVRF) in young adult survivors of childhood
acute lymphoblastic leukemia (ALL). Patients and Methods Twenty-six subjects (median age…

GITR [glucocorticoid inducible tumor necrosis factor receptor (TNFR)‐related protein] and 4‐1BB
are costimulatory TNFR family members that are expressed on regulatory and effector T …

Methamphetamines are a popular class of recreational drugs sometimes abused by women
of childbearing age. The effects of methamphetamine abuse on pregnancy outcome and …

Cocaine abuse during pregnancy has been reported to be associated with a variety of fetal
complications and with preterm labor. In this cohort study, pregnancy outcome and health …

The regulation of T cell expansion by TNFR family members plays an important role in
determining the magnitude of the immune response to pathogens. As several members of the …

The goal of postmastectomy breast reconstruction is to restore a woman’s body image and
to satisfy her personal expectations regarding the results of surgery. Studies in other surgical …

CD8 + T cell exhaustion impedes control of chronic viral infection; yet how new T cell
responses are mounted during chronic infection is unclear. Unlike T cells primed at the onset of …