Cerebrospinal fluid biomarkers to stratify injury severity and predict outcome in human traumatic spinal cord injury
…, VK Noonan, LM Bélanger, L Ritchie… - Journal of …, 2017 - liebertpub.com
Neurologic impairment after spinal cord injury (SCI) is currently measured and classified by
functional examination. Biological markers that objectively classify injury severity and predict …
functional examination. Biological markers that objectively classify injury severity and predict …
Spinal cord perfusion pressure predicts neurologic recovery in acute spinal cord injury
JW Squair, LM Bélanger, A Tsang, L Ritchie… - Neurology, 2017 - AAN Enterprises
Objective: To determine whether spinal cord perfusion pressure (SCPP) as measured with a
lumbar intrathecal catheter is a more predictive measure of neurologic outcome than the …
lumbar intrathecal catheter is a more predictive measure of neurologic outcome than the …
Predicting injury severity and neurological recovery after acute cervical spinal cord injury: a comparison of cerebrospinal fluid and magnetic resonance imaging …
…, K Dong, L Belanger, L Ritchie… - Journal of …, 2018 - liebertpub.com
Biomarkers of acute human spinal cord injury (SCI) could provide a more objective measure
of spinal cord damage and a better predictor of neurological outcome than current …
of spinal cord damage and a better predictor of neurological outcome than current …
Empirical targets for acute hemodynamic management of individuals with spinal cord injury
JW Squair, LM Bélanger, A Tsang, L Ritchie… - Neurology, 2019 - AAN Enterprises
Objective To determine the hemodynamic conditions associated with optimal neurologic
improvement in individuals with acute traumatic spinal cord injury (SCI) who had lumbar …
improvement in individuals with acute traumatic spinal cord injury (SCI) who had lumbar …
Association of CSF and serum neurofilament light and glial fibrillary acidic protein, Injury Severity, and Outcome in spinal cord Injury
…, J Gill, N Fallah, MA Skinnider, L Belanger, L Ritchie… - Neurology, 2023 - AAN Enterprises
Background and Objectives Traumatic spinal cord injury (SCI) is highly heterogeneous, and
tools to better delineate pathophysiology and recovery are needed. Our objective was to …
tools to better delineate pathophysiology and recovery are needed. Our objective was to …
A targeted proteomics analysis of cerebrospinal fluid after acute human spinal cord injury
…, A Prudova, L Belanger, L Ritchie… - Journal of …, 2017 - liebertpub.com
Efforts to validate novel therapies in acute clinical trials for spinal cord injury (SCI) are impeded
by the lack of objective quantitative measures that reflect injury severity and accurately …
by the lack of objective quantitative measures that reflect injury severity and accurately …
[HTML][HTML] Proteomic portraits reveal evolutionarily conserved and divergent responses to spinal cord injury
…, K Dong, F Streijger, L Belanger, L Ritchie… - Molecular & Cellular …, 2021 - ASBMB
Despite the emergence of promising therapeutic approaches in preclinical studies, the failure
of large-scale clinical trials leaves clinicians without effective treatments for acute spinal …
of large-scale clinical trials leaves clinicians without effective treatments for acute spinal …
Characterization of cerebrospinal fluid ubiquitin C-terminal hydrolase L1 as a biomarker of human acute traumatic spinal cord injury
…, J Gill, J Cooper, L Belanger, L Ritchie… - Journal of …, 2021 - liebertpub.com
A major obstacle for translational research in acute spinal cord injury (SCI) is the lack of
biomarkers that can objectively stratify injury severity and predict outcome. Ubiquitin C-terminal …
biomarkers that can objectively stratify injury severity and predict outcome. Ubiquitin C-terminal …
All over the MAP: describing pressure variability in acute spinal cord injury
CM Gee, A Tsang, LM Bélanger, L Ritchie, T Ailon… - Spinal Cord, 2022 - nature.com
Study design Observational study. Objectives To examine the feasibility of meeting the
current clinical guidelines for the hemodynamic management of acute spinal cord injury (SCI) …
current clinical guidelines for the hemodynamic management of acute spinal cord injury (SCI) …
[HTML][HTML] Characterization of hyperacute neuropathic pain after spinal cord injury: a prospective study
J Rosner, M Negraeff, LM Bélanger, A Tsang, L Ritchie… - The journal of pain, 2022 - Elsevier
There is currently a lack of information regarding neuropathic pain in the very early stages
of spinal cord injury (SCI). In the present study, neuropathic pain was assessed using the …
of spinal cord injury (SCI). In the present study, neuropathic pain was assessed using the …