The pool of microbes inhabiting our body is known as “microbiota” and their collective
genomes as “microbiome”. The colon is the most densely populated organ in the human body, …

Contents Despite major efforts directed at improving the yield of blastocysts from immature
oocytes in vitro, the quality of such blastocysts continually lags behind that of blastocysts …

Non-alcoholic fatty liver disease (NAFLD) in children is becoming a major health concern. A
“multiple-hit” pathogenetic model has been suggested to explain the progressive liver …

Background T-cell large granular lymphocytic leukemia is a rare lymphoproliferative disorder
characterized by the expansion of clonal CD3+CD8+ cytotoxic T lymphocytes (CTLs) and …

Zonulin, a protein that modulates intestinal permeability, is upregulated in several autoimmune
diseases and is involved in the pathogenesis of autoimmune diabetes in the BB/Wor …

Background In patients with acquired aplastic anemia, destruction of hematopoietic cells by
the immune system leads to pancytopenia. Patients have a response to immunosuppressive …

Background and aims: Despite the progress made in understanding the immunological
aspects of the pathogenesis of coeliac disease (CD), the early steps that allow gliadin to cross …

Most cases of adult myeloid neoplasms are routinely assumed to be sporadic. Here, we
describe an adult familial acute myeloid leukemia (AML) syndrome caused by germline …

The steroid hormone progesterone (P4) plays a key role in the reproductive events associated
with pregnancy establishment and maintenance. High concentrations of circulating P4 in …

Chronic lymphoproliferative disorders of natural killer cells (CLPD-NKs) and T-cell large
granular lymphocytic leukemias (T-LGLs) are clonal lymphoproliferations arising from either …