User profiles for M. Fehlings.

Michael Fehlings

ImmunoScape
Verified email at immunoscape.com
Cited by 3269

Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms

CH Tator, MG Fehlings - Journal of neurosurgery, 1991 - thejns.org
… Several experimental models have been developed to simulate the compression type of
acute cord trauma (for a review see Fehlings and Tator“); the first of these was the weight-…

Epidemiology, demographics, and pathophysiology of acute spinal cord injury

LHS Sekhon, MG Fehlings - Spine, 2001 - journals.lww.com
Fehlings, it is now generally accepted that acute SCI is a two-step process involving primary
and secondary mechanisms. The primary mechanism involves the initial mechanical injury …

[HTML][HTML] Traumatic spinal cord injury

…, M Kotter, C Druschel, A Curt, MG Fehlings - Nature reviews Disease …, 2017 - nature.com
… with permission of AlphaMed Press, from Concise review: bridging the gap: novel
neuroregenerative and neuroprotective strategies in spinal cord injury, Ahuja, CS & Fehlings, M., …

Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury: results of the third national acute …

…, L Leo-Summers, EF Aldrich, M Fazl, M Fehlings… - Jama, 1997 - jamanetwork.com
Objective. —To compare the efficacy of methylprednisolone administered for 24 hours with
methyprednisolone administered for 48 hours or tirilazad mesylate administered for 48 hours …

Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates

Y Simoni, E Becht, M Fehlings, CY Loh, SL Koo… - Nature, 2018 - nature.com
Various forms of immunotherapy, such as checkpoint blockade immunotherapy, are proving
to be effective at restoring T cell-mediated immune responses that can lead to marked and …

A new classification of thoracolumbar injuries: the importance of injury morphology, the integrity of the posterior ligamentous complex, and neurologic status

…, R Hedlund, J Harrop, M Dvorak, K Wood, MG Fehlings… - Spine, 2005 - journals.lww.com
Study Design. A new proposed classification system for thoracolumbar (TL) spine injuries,
including injury severity assessment, designed to assist in clinical management. Objective. To …

A novel classification system for spinal instability in neoplastic disease: an evidence-based approach and expert consensus from the Spine Oncology Study Group

…, CI Shaffrey, SH Berven, JS Harrop, MG Fehlings… - Spine, 2010 - journals.lww.com
Study Design. Systematic review and modified Delphi technique. Objective. To use an
evidence-based medicine process using the best available literature and expert opinion …

[HTML][HTML] Early versus delayed decompression for traumatic cervical spinal cord injury: results of the Surgical Timing in Acute Spinal Cord Injury Study (STASCIS)

MG Fehlings, A Vaccaro, JR Wilson, A Singh… - PloS one, 2012 - journals.plos.org
Background There is convincing preclinical evidence that early decompression in the setting
of spinal cord injury (SCI) improves neurologic outcomes. However, the effect of early …

[HTML][HTML] Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical …

…, BH Dobkin, LA Havton, PH Ellaway, MG Fehlings… - Spinal cord, 2007 - nature.com
The International Campaign for Cures of Spinal Cord Injury Paralysis (ICCP) supported an
international panel tasked with reviewing the methodology for clinical trials in spinal cord …

Global prevalence and incidence of traumatic spinal cord injury

…, S Kalsi-Ryan, A Nouri, MG Fehlings - Clinical …, 2014 - Taylor & Francis
Background Spinal cord injury (SCI) is a traumatic event that impacts a patient’s physical,
psychological, and social well-being and places substantial financial burden on health care …