Lupeol Long-Chain Fatty Acid Esters with Antimalarial Activity from Holarrhena floribunda

J Fotie, DS Bohle, ML Leimanis… - Journal of Natural …, 2006 - ACS Publications
… Its ESIMS spectrum (positive ion mode) displayed a molecular peak at m/z 759 ([M + + Na
+ ], [M + ] m/z 736), an observation confirmed on its EIMS by the signal at m/z 737 ([M + + H]). …

[HTML][HTML] Effective and cheap removal of leukocytes and platelets from Plasmodium vivax infected blood

…, S Kaewpongsri, R Suwanarusk, ML Leimanis… - Malaria journal, 2009 - Springer
Background Investigations of Plasmodium vivax are restricted to samples collected from
infected persons or primates, because this parasite cannot be maintained in in vitro cultures. …

[HTML][HTML] Evaluation of three parasite lactate dehydrogenase-based rapid diagnostic tests for the diagnosis of falciparum and vivax malaria

…, K Htun, J Luchavez, C Dureza, S Proux, M Leimanis… - Malaria journal, 2009 - Springer
Background In areas where non-falciparum malaria is common rapid diagnostic tests (RDTs)
capable of distinguishing malaria species reliably are needed. Such tests are often based …

Modulation of GSH levels in ABCC1 expressing tumor cells triggers apoptosis through oxidative stress

…, J Karwatsky, MC Lincoln, ML Leimanis… - Biochemical …, 2007 - Elsevier
The over-expression of ABCC1 transmembrane protein has been shown to cause multidrug
resistance in tumor cell lines. ABCC1 is a member of the ABC transmembrane proteins that …

[HTML][HTML] High-density blood transcriptomics reveals precision immune signatures of SARS-CoV-2 infection in hospitalized individuals

…, B Feldmann, L Teng, T McBride, ML Leimanis… - Frontiers in …, 2021 - frontiersin.org
The immune response to COVID-19 infection is variable. How COVID-19 influences clinical
outcomes in hospitalized patients needs to be understood through readily obtainable …

[HTML][HTML] Sensitive detection of malaria infection by third harmonic generation imaging

JM Bélisle, S Costantino, ML Leimanis, MJ Bellemare… - Biophysical journal, 2008 - cell.com
Malaria remains a major health concern worldwide, with 350–500million cases reported
annually in endemic countries. In this study, we report a novel and highly sensitive optical-…

[HTML][HTML] Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand

…, ME Boel, B Russell, M Imwong, ML Leimanis… - Malaria journal, 2011 - Springer
Chloroquine (CQ) resistant vivax malaria is spreading. In this case, Plasmodium vivax
infections during pregnancy and in the postpartum period were not satisfactorily cleared by CQ, …

[HTML][HTML] Considerations on the use of nucleic acid-based amplification for malaria parasite detection

…, M Barends, J Zwang, RN Price, M Leimanis… - Malaria journal, 2011 - Springer
Background Nucleic acid amplification provides the most sensitive and accurate method to
detect and identify pathogens. This is primarily useful for epidemiological investigations of …

Lipid profiling and dietary assessment of infant formulas reveal high intakes of major cholesterol oxidative product (7-ketocholesterol)

A Kilvington, C Barnaba, S Rajasekaran, MLL Leimanis… - Food Chemistry, 2021 - Elsevier
… One mL of hexane and 2 mL of 2 M NaCl were added to the samples and then shaken
vigorously. The methylated fraction was collected and diluted 200-fold. One µL was injected into a …

[HTML][HTML] Long-term storage limits PCR-based analyses of malaria parasites in archival dried blood spots

J Hwang, J Jaroensuk, ML Leimanis, B Russell… - Malaria journal, 2012 - Springer
Background Blood samples collected in epidemiological and clinical investigations and then
stored, often at room temperature, as blood spots dried on a filter paper have become one …