User profiles for M. Tun-Abraham

ME Tun-Abraham

Western University, London Ontario
Verified email at uwo.ca
Cited by 712

MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their …

…, A Memarnejadian, PA Szabo, ME Tun-Abraham… - PLoS …, 2017 - journals.plos.org
Superantigens (SAgs) are potent exotoxins secreted by Staphylococcus aureus and Streptococcus
pyogenes. They target a large fraction of T cell pools to set in motion a “cytokine storm…

Defining benchmark outcomes for ALPPS

…, M Tun-Abraham, V Ardiles, M Malago… - Annals of …, 2019 - journals.lww.com
Objective: The aim of this study was to use the concept of benchmarking to establish robust
and standardized outcome references after the procedure ALPPS (Associating Liver Partition …

Mucosa-associated invariant T cells infiltrate hepatic metastases in patients with colorectal carcinoma but are rendered dysfunctional within and adjacent to tumor …

CR Shaler, ME Tun-Abraham, AI Skaro… - Cancer Immunology …, 2017 - Springer
Mucosa-associated invariant T (MAIT) cells are innate-like T lymphocytes that are unusually
abundant in the human liver, a common site of colorectal carcinoma (CRC) metastasis. …

Intermediate-term survival and quality of life outcomes in patients with advanced colorectal liver metastases undergoing associating liver partition and portal vein …

KN Wanis, V Ardiles, FA Alvarez, ME Tun-Abraham… - Surgery, 2018 - Elsevier
Background Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS)
is an innovative, 2-staged hepatectomy which has elicited controversy within the …

[HTML][HTML] Subnormothermic oxygenated perfusion optimally preserves donor kidneys ex vivo

…, L Jiang, S Aquil, H Sharma, ME Tun-Abraham… - Kidney International …, 2019 - Elsevier
Introduction The current methods of preserving donor kidneys in nonoxygenated cold conditions
minimally protect the kidney against ischemia-reperfusion injury (IRI), a major source of …

[HTML][HTML] Surgical treatment of pancreatic pseudocysts

…, N Franco-Guerrero, M Tun-Abraham… - Cirugía y Cirujanos …, 2016 - Elsevier
Background A pancreatic pseudocyst is the collection of pancreatic secretions surrounded
by fibrous tissue caused by pancreatic disease that affects the pancreatic duct. Clinical …

[HTML][HTML] Management of colorectal cancer with synchronous liver metastases: impact of multidisciplinary case conference review

…, K Pineda-Solis, ME Tun-Abraham… - … Surgery and Nutrition, 2017 - ncbi.nlm.nih.gov
Background While no evidence exists to support mandatory multidisciplinary case conference
(MCC) review for patients with synchronous colorectal cancer and liver metastases, this …

[HTML][HTML] Acute pancreatitis associated with hypercalcaemia

ME Tun-Abraham, G Obregón-Guerrero… - Cirugía y Cirujanos …, 2015 - Elsevier
Background Hypercalcaemia due to primary hyperparathyroidism is a rare cause of acute
pancreatitis, with a reported prevalence of 1.5–8%. There is no clear pathophysiological basis, …

Patient survival after simultaneous ALPPS and colorectal resection

…, M Linecker, V Ardiles, ME TunAbraham… - World journal of …, 2017 - Wiley Online Library
Background Liver resection combined with colorectal surgery (CRS) is the only curative
option in many patients presenting with synchronous colorectal cancer and liver metastases (…

[HTML][HTML] Bidirectional graft-host hematological traffic in liver transplantation

H Sharma, ME Tun-Abraham… - Hepatobiliary Surgery and …, 2019 - ncbi.nlm.nih.gov
The highly complex immuno-hematological system of the recipient has to rebalance itself
when the liver is replaced with a graft that has its own system. This gives us an opportunity for …