There is an urgent need for both the scientific development and clinical validation of novel
therapies for acute spinal cord injury (SCI). The scientific development of novel therapies …

Study Design. Prospective clinical study. Objective. To assess Health-Related Quality of Life
outcomes in patients undergoing surgery for spinal metastases. Summary of Background …

Object Ischemia is an important factor in the pathophysiology of secondary damage after
traumatic spinal cord injury (SCI) and, in the setting of thoracoabdominal aortic aneurysm repair…

Neurologic impairment after spinal cord injury (SCI) is currently measured and classified by
functional examination. Biological markers that objectively classify injury severity and predict …

Study Design. Prospective cohort study. Objectives. To prospectively validate the application
of appendicular surgical oncology principles to the treatment of primary bone tumors of the …

Background context Thoracolumbar burst fractures have good outcomes when treated with
early ambulation and orthosis (TLSO). If equally good outcomes could be achieved with early …

Object Unilateral facet injuries can be treated with either anterior or posterior fixation techniques
with reportedly good outcomes. The two approaches have not been directly compared, …

Study Design. Multicenter ambispective cohort analysis. Objective. The purpose of this study
is to determine whether applying Enneking's principles to surgical management of primary …

Study design: Prospective cohort study. Objectives: To characterize the cerebrospinal fluid (CSF)
concentrations of glial fibrillary acidic protein, neuron specific enolase (NSE), S-100β, …

BACKGROUND CONTEXT: There is very little evidence to guide treatment of patients with
spinal surgical site infection (SSI) who require irrigation and debridement (I&D) in deciding …