Recombinant protein therapeutics, vaccines, and plasma products have a long record of
safety. However, the use of cell culture to produce recombinant proteins is still susceptible to …

… Wiebe, unpublished observations). Our experiments do suggest that other MAFs were
either not consistently present in active amounts in the lymphoid supernatants we studied, or if …

Use of the organic solvent, tri(n‐butyl)phosphate (TNBP), and detergents for the inactivation
of viruses in labile blood derivatives was evaluated by addition of marker viruses (VSV, …

Cytokines affecting mononuclear phagocytes were screened for activation of human
macrophages to secrete H2O2 and kill toxoplasmas. In contrast to recombinant interferon-gamma (…

Since 1966, the Subcommittee on Interrelationships Among Catalogued Arboviruses (SIRACA),
a subcommittee of the American Committee on Arthropod-borne Viruses, has attempted …

A monoclonal antibody (MAb/T2G1s) was prepared by fusion using spleen cells from mice
immunized with the NH 2 -terminal CNBr fragment of human fibrin II, the so-called (T)N-DSK [(…

Two morphologically distinct cell types of Coxiella burneti phase I have been separated on
the basis of unique buoyant densities. When centrifuged to equilibrium in cesium chloride or …

The thermal inactivation of viruses in labile blood derivatives was evaluated by addition of
marker viruses (VSV, Sindbis, Sendai, EMC) to anti‐hemophilic factor (AHF) concentrates. …

Decisions by regulatory authorities to permit clinical trials or marketing of cell culture-derived
biologicals are based on assessment of benefits and risks associated with use of the …

Background Quality in health care can be evaluated using quality indicators (QIs). Elements
contained in the surgical operative report are potential sources for QI data, but little is known …