… at doses of 1.02−18.53 μg/mL when tested in vitro against two … μg/mL, while the ethanolic
extract appeared to be the most active against Sierra Leone (D-6), with an IC 50 of 4.33 μg/mL. …

… Furthermore, in our experience the quantity of CF11 powder per ml of whole blood, the degree
of column compaction, as well as the amount and extent of washing, influence the efficacy …

… The MTT dye was added to a final concentration of 50 μg/mL and cells were then incubated
for another 4 h at 37 C. The media containing residual MTT dye was carefully aspirated from …

The immune response to COVID-19 infection is variable. How COVID-19 influences clinical
outcomes in hospitalized patients needs to be understood through readily obtainable …

Malaria remains a major health concern worldwide, with 350–500million cases reported
annually in endemic countries. In this study, we report a novel and highly sensitive optical-…

… = 20.6, D71 = 10.8 and D143 = 7.9 ng/ml) indicated adequate drug exposure and were around
the 15 ng/ml serum threshold considered therapeutic against CQ-susceptible parasites[15…

Background Blood samples collected in epidemiological and clinical investigations and then
stored, often at room temperature, as blood spots dried on a filter paper have become one …

Precision medicine requires the translation of basic biological understanding to medical
insights, mainly applied to characterization of each unique patient. In many clinical settings, this …

Background Multiple organ dysfunction syndrome (MODS) occurs in the setting of a variety
of pathologies including infection and trauma. Some patients decompensate and require …

… At least 1.25 mL of blood was collected in EDTA tubes followed by transfer to a PAXgene
tube at 1:2.5 mixture with stabilizing agent. Data, deidentified and paired to RNA sample, was …