… The most generic procedure used today involves separation of an extract using reversed-phase
HPLC and splitting of the eluent postcolumn into a mass spectrometer (usually MS/MS to …

… (Δ 9 -THC) 1 and cannabidol 2, which was first launched in Canada in April 2005 as an
adjunctive treatment for the symptomatic relief of neuropathic pain in multiple sclerosis (MS) …

… Mark Butler received a BSc (Hons) and PhD, with a focus on marine sponges, from The
University of Melbourne in 1992. After postdoctoral work with Professor Pettit at the Arizona State …

The NOD-like receptor (NLR) family, pyrin domain–containing protein 3 (NLRP3) inflammasome
is a component of the inflammatory process, and its aberrant activation is pathogenic in …

Covering: 2008–2013. Previous review: 2008, 25, 475 There are a significant number of
natural product (NP) drugs in development. We review the 100 NP and NP-derived compounds …

Parkinson’s disease (PD) is characterized by a profound loss of dopaminergic neurons in
the substantia nigra, accompanied by chronic neuroinflammation, mitochondrial dysfunction, …

Natural products have played a pivotal role in antibiotic drug discovery with most antibacterial
drugs being derived from a natural product or natural product lead. However, the rapid …

The continued emergence of multi-drug-resistant bacteria is a major public health concern.
The identification and development of new antibiotics, especially those with new modes of …

PURPOSE: There is a perception that the standard of care is to repair hip fractures surgically
within 24 hours of hospitalization. However, it is unclear whether this reduces mortality or …

There is growing global recognition that the continued emergence of multidrug-resistant
bacteria poses a serious threat to human health. Action plans released by the World Health …