BACKGROUND Treatment of acute trauma coagulopathy has shifted toward rapid replacement
of coagulation factors with frozen plasma (FP). There are logistic difficulties in providing …

During the Great War, Canadian military surgeons produced some of the greatest innovations
to improve survival on the battlefield. Arguably, the most important was bringing blood …

Chromatin remodeling by Polycomb group (PcG) and trithorax group (trxG) proteins regulates
gene expression in all metazoans. Two major complexes, Polycomb repressive complexes …

… The first week is in lecture and laboratory format, whereas the major goal of the second
week is to confirm these skills in increasingly complex scenarios using simulation. Like in the …

Transcriptional silencing of retroviruses poses a major obstacle to their use as gene therapy
vectors. Silencing is most pronounced in stem cells which are desirable targets for …

… determined with respect to the expressed mouse β‐major gene (Table I). These calculations
… silenced BGT32 transgenic mice compared with the expressed mouse β‐major globin gene …

Medical support to deployed field forces is increasingly becoming a shared responsibility
among allied nations. National military medical planners face several key challenges, …

… The major causes of death were torso exsanguination, neurologic injury, and gross
mutilation. Relatively few deaths were deemed potentially preventable. Based on these data, we …

… The major limitation to this study is the small number of participants. Future studies need to
… Furthermore, another major limitation is that the structured evaluations used as our primary …

Silencing of retrovirus vectors poses a significant obstacle to genetic manipulation of stem
cells and their use in gene therapy. We describe a mammalian silencer blocking assay using …