17, 18-Epoxyeicosatetraenoic Acid Targets PPARγ and p38 Mitogen–Activated Protein Kinase to Mediate Its Anti-inflammatory Effects in the Lung: Role of soluble …

C Morin, M Sirois, V Échavé, R Albadine… - American journal of …, 2010 - atsjournals.org
This study sought to assess putative pathways involved in the anti-inflammatory effects of 17,18-epoxyeicosatetraenoic
acid (17,18-EpETE), as measured by a decrease in the …

Lipoxin generation is related to soluble epoxide hydrolase activity in severe asthma

…, R Khaddaj-Mallat, M Sirois, C Sirois… - American journal of …, 2014 - atsjournals.org
Rationale: Severe asthma is characterized by airway inflammatory responses associated
with aberrant metabolism of arachidonic acid. Lipoxins (LX) are arachidonate-derived pro-…

EET displays anti-inflammatory effects in TNF-α–stimulated human bronchi: putative Role of CPI-17

C Morin, M Sirois, V Echave, MM Gomes… - American journal of …, 2008 - atsjournals.org
The aim of the present study was to investigate the anti-inflammatory effects of 14,15-epoxyeicosatrienoic
acid (EET) on reactivity and Ca 2+ sensitivity in TNF-α–stimulated human …

Relaxing effects of 17 (18)-EpETE on arterial and airway smooth muscles in human lung

C Morin, M Sirois, V Echave… - American Journal of …, 2009 - journals.physiology.org
Human cytochrome P-450 epoxygenase enzymes metabolize eicosapentaenoic acid (EPA),
an ω-3-polyunsaturated fatty acid (PUFA), and leads to the production of 17(18)-…

The hand-held ultrasound examination for penetrating abdominal trauma

AW Kirkpatrick, M Sirois, CG Ball, KB Laupland… - The American journal of …, 2004 - Elsevier
BACKGROUND: An evaluation of hand-held ultrasonography (US) in the assessment of
penetrating torso trauma has not yet been reported. METHODS: A 2.4 kg hand-held ultrasound …

Occult pneumothoraces in critical care: a prospective multicenter randomized controlled trial of pleural drainage for mechanically ventilated trauma patients with occult …

…, S Rizoli, JF Ouellet, DJ Roberts, M Sirois… - Journal of Trauma …, 2013 - journals.lww.com
BACKGROUND Patients with an occult pneumothoraces (OPTXs) may be at risk of tension
pneumothoraces (TPTXs) without drainage or pleural drainage complications if treated. …

[HTML][HTML] Prospective evaluation of hand-held focused abdominal sonography for trauma (FAST) in blunt abdominal trauma

AW Kirkpatrick, M Sirois, KB Laupland… - Canadian journal of …, 2005 - ncbi.nlm.nih.gov
Background Ultrasonography (US) has become indispensable in assessing the status of the
injured patient. Although hand-held US equipment is now commercially available and may …

Resolvin E1 normalizes contractility, Ca2+ sensitivity and smooth muscle cell migration rate in TNF-α- and IL-6-pretreated human pulmonary arteries

…, S Marouan, C Sirois, M Sirois… - … of Physiology-Lung …, 2015 - journals.physiology.org
Pulmonary hypertension (PH) is a rare disease in which pathophysiology is characterized
by an increase in proinflammatory mediators, chronic endothelial dysfunctions, and a high …

Surgical management of sternoclavicular joint infection

…, A Deshaies, C Sirois, M Sirois - European journal of …, 2011 - academic.oup.com
Objective: Sternoclavicular joint (SCJ) infections are rarely encountered and their management
is not well standardised. We reviewed our experience with the management of this …

Resolvin D1 reverses reactivity and Ca2+ sensitivity induced by ET-1, TNF-α, and IL-6 in the human pulmonary artery

…, E Rizcallah, C Sirois, M Sirois… - American Journal …, 2014 - journals.physiology.org
Pulmonary hypertension (PH) is a rare and progressive disease characterized by an inflammatory
status and vessel wall remodeling, resulting in increased pulmonary artery resistance. …