In this update of the Canadian Cardiovascular Society heart failure (HF) guidelines, we provide
comprehensive recommendations and practical tips for the pharmacologic management …

In this update, we focus on selected topics of high clinical relevance for health care providers
who treat patients with heart failure (HF), on the basis of clinical trials published after 2017. …

Objectives This study evaluated the impact of clinical and physiological factors limiting
treatment optimization toward recommended medical therapy in heart failure (HF). Background …

Importance The period following heart failure hospitalization (HFH) is a vulnerable time with
high rates of death or recurrent HFH. Objective To evaluate clinical characteristics, outcomes…

Cardiac amyloidosis is an under-recognized and potentially fatal cause of heart failure and
other cardiovascular manifestations. It is caused by deposition of misfolded precursor …

Aortic regurgitation (AR) developing while using a continuous-flow left ventricular assist
device (CF-LVAD) affects 25% to 30% of patients within the first year of implantation and is …

Objectives : This study investigated temporal changes in the demographics and the prognosis
of cardiac allograft vasculopathy (CAV) over 30 years following heart transplantation (HTx)…

Background Conversations about goals of care in hospital are important to patients who
have advanced heart failure (HF). Methods We conducted a multicenter survey of cardiology …

Background Pyrophosphate (PYP) scintigraphy provides high diagnostic accuracy for the
detection of transthyretin (ATTR) cardiac amyloidosis (CA). There has recently been emerging …

Background Use of health administrative databases is proposed for screening and monitoring
of participants in randomized registry trials. However, access to these databases raises …