Background Cabozantinib is approved for metastatic renal cell carcinoma (mRCC) based on
the METEOR and CABOSUN trials. However, real‐world effectiveness and dosing patterns …

The business model canvas is a popular tool used to develop value-driven business models.
Specific emphasis is placed on understanding what customers value and providing users …

Left atrial appendage aneurysm (LAAA) is a rare cardiac pathology that is often identified in
adulthood. There are a myriad of presentations related to atrial appendage enlargement, but …

Introduction The unique evidentiary, economic and ethical challenges associated with
health technology assessment (HTA) of precision therapies limit access to novel drugs and …

Abstract Characterization of the pluripotent “ground state” has led to a greater understanding
of species-specific stem cell differences and has imparted an appreciation of the …

Pharmacogenomics (PGx)‐based personalized medicine (PM) is increasingly utilized to
guide treatment decisions for many drug‐disease combinations. Notably, London Health …

Precision health aims to personalize treatment and prevention strategies based on individual
genetic differences. While it has significantly improved healthcare for specific patient …

Simple Summary All cancers must maintain telomere length to achieve immortality and
around 80% do so by reactivating the enzyme complex telomerase. The diverse regulatory …

The rapid development of metastatic melanoma treatment options has significantly improved
overall survival, but paralleled patient educational and supportive care resources have …

639 Background: Cabozantinib (Cabo) is approved for mRCC patients based on the METEOR
and CABOSUN trials. The real-world effectiveness of Cabo in mRCC patients in the first- (…