Tumor protein p53 (TP53) is the most frequently mutated gene in cancer 1 , 2 . In patients with
myelodysplastic syndromes (MDS), TP53 mutations are associated with high-risk disease …

Background A limited number of attempts have been made to develop a questionnaire that
assesses the experience of motion sickness. Further, many available questionnaires quantify …

Cell-free protein synthesis (CFPS) is a platform technology that provides new opportunities
for protein expression, metabolic engineering, therapeutic development, education, and more…

The goal of therapy for patients with essential thrombocythemia (ET) and polycythemia vera
(PV) is to reduce thrombotic events by normalizing blood counts. Hydroxyurea (HU) and …

Background: Nausea that develops during the period that begins 24 hours after the administration
of chemotherapy is called delayed nausea, and occurs in many patients with cancer. …

Methods: We conducted a retrospective review of all urethroplasties performed at a Canadian
tertiary referral centre from 2003 to 2012. Failure was defined as a recurrent stricture< 16 …

Over the last 50 years, Cell-Free Protein Synthesis (CFPS) has emerged as a powerful
technology to harness the transcriptional and translational capacity of cells within a test tube. By …

Myeloproliferative neoplasms (MPN) that have evolved into accelerated or blast phase disease
(MPN-AP/BP) have poor outcomes with limited treatment options and therefore represent …

Clinical recommendations for Acute Myeloid Leukemia (AML) classification and risk-stratification
remain heavily reliant on cytogenetic findings at diagnosis, which are present in< 50% …

Recent genomic research efforts in multiple myeloma have revealed clinically relevant
molecular subgroups beyond conventional cytogenetic classifications. Implementing these …