Recent advances in genetics, diagnosis, localization, and treatment of pheochromocytoma

…, WM Linehan, G Eisenhofer, MCM Walther… - Annals of internal …, 2001 - acpjournals.org
Pheochromocytoma is a rare but important tumor of chromaffin cells that is frequently considered
in the evaluation of hypertension, arrhythmias, or panic disorder and in the follow-up of …

The genetic basis of cancer of the kidney

WM Linehan, MM Walther, B Zbar - The Journal of urology, 2003 - auajournals.org
Purpose : The types of epithelial renal tumors are clear cell, types I and II papillary,
chromophobe and oncocytoma. We identified the genetic basis of these different types of kidney …

von Recklinghausen′ s disease and pheochromocytomAS

MCM Walther, J Herring, E Enquist, HR Keiser… - The Journal of …, 1999 - Elsevier
PURPOSE:: We review the literature and characterize the clinical findings of von
Recklinghausen’sassociated pheochromocytoma. MATERIALS AND METHODS:: A Grateful Med …

Identification of the von Hippel-Lindau disease tumor suppressor gene

…, MCM Walther, Y Weng, DSR Duan, M Dean… - Science, 1993 - science.org
A gene discovered by positional cloning has been identified as the von Hippel-Lindau (VHL)
disease tumor suppressor gene. A restriction fragment encompassing the gene showed …

Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

…, M Bernues, S Richard, CJM Lips, MCM Walther… - Nature …, 1997 - nature.com
Hereditary papillary renal carcinoma (HPRC) is a recently recognized form of inherited
kidney cancer characterized by a predisposition to develop multiple, bilateral papillary renal …

Biochemical diagnosis of pheochromocytoma: which test is best?

…, K Pacak, MCM Walther, WM Linehan, M Mannelli… - Jama, 2002 - jamanetwork.com
ContextDiagnosis of pheochromocytoma depends on biochemical evidence of catecholamine
production by the tumor. However, the best test to establish the diagnosis has not been …

Renal tumors in the Birt-Hogg-Dube syndrome

CP Pavlovich, MCM Walther, RA Eyler… - The American journal …, 2002 - journals.lww.com
Birt-Hogg-Dubé (BHD) syndrome is an autosomal dominant genodermatosis characterized
by the development of small dome-shaped papules on the face, neck, and upper trunk (…

[PDF][PDF] Mutations in the fumarate hydratase gene cause hereditary leiomyomatosis and renal cell cancer in families in North America

…, P Choyke, P Stratton, M Merino, MCM Walther… - The American Journal of …, 2003 - cell.com
Hereditary leiomyomatosis and renal cell cancer (HLRCC) is an autosomal dominant
disorder characterized by smooth-muscle tumors of the skin and uterus and/or renal cancer. …

Cyclophosphamide-induced cystitis and bladder cancer in patients with Wegener granulomatosis

C Talar-Williams, YM Hijazi, MCM Walther… - Annals of Internal …, 1996 - acpjournals.org
Objective: To describe the incidence of, clinical manifestations of, and risk factors for
cyclophosphamide-induced urinary bladder toxicity in patients treated for nonmalignant disease. …

Biochemical diagnosis of pheochromocytoma: how to distinguish true-from false-positive test results

…, DS Goldstein, MCM Walther… - The Journal of …, 2003 - academic.oup.com
Measurements of plasma normetanephrine and metanephrine provide a highly sensitive
test for diagnosis of pheochromocytoma, but false-positive results remain a problem. We …