The tissue-specific pattern of mRNA expression can indicate important clues about gene
function. High-density oligonucleotide arrays offer the opportunity to examine patterns of gene …

High-throughput gene expression profiling has become an important tool for investigating
transcriptional activity in a variety of biological samples. To date, the vast majority of these …

Although practiced clinically for more than 40 years, the use of hematopoietic stem cell (HSC)
transplants remains limited by the ability to expand these cells ex vivo. An unbiased …

In transgenic mice, self-reactive B lymphocytes are elimlnated if they encounter membrane-bound
self antlgene during their development within the bone marrow. We show here that …

Here we have identified 'triple D' (3d), a recessive N-ethyl-N-nitrosourea-induced mutation
and phenotype in which no signaling occurs via the intracellular Toll-like receptors 3, 7 and 9 (…

THE recessive mouse mutations lpr and gld create deficiencies in an interacting pair of cell
surface molecules, CD95 (Fas/APO-1) and Fas-ligand (FasL), respectively 1–3 , resulting in …

As fabrication technology pushes the dimensions of ferromagnetic structures into the
nanoscale, understanding the magnetization processes of these structures is of fundamental …

New opportunities in mammalian functional genomics are emerging through the combination
of high throughput technology and methods that allow manipulation of gene expression in …

We demonstrate movement of a head-to-head domain wall through a magnetic nanowire of
permalloy (Ni 81 Fe 19) simply by passing an electrical current through the domain wall and …

Considerable evidence supports the hypothesis that the nonreceptor protein tyrosine kinase
p59’r” participates in signal transduction from the T cell receptor (TCR). To examine this …