Mechanical forces are central to developmental, physiological and pathological processes
1 . However, limited understanding of force transmission within sub-cellular structures is a …

In the absence of perfusable vascular networks, three-dimensional (3D) engineered tissues
densely populated with cells quickly develop a necrotic core 1 . Yet the lack of a general …

We report the establishment of a library of micromolded elastomeric micropost arrays to
modulate substrate rigidity independently of effects on adhesive and other material surface …

Actomyosin contractility affects cellular organization within tissues in part through the
generation of mechanical forces at sites of cell–matrix and cell–cell contact. While increased …

A systematic investigation of the direction and degree of stereoselectivity in aldol addition
reactions is presented involving achiral unsubstituted metal enolate and enolsilane …

In he past decade, object detection has achieved significant progress in natural images but
not in aerial images, due to the massive variations in the scale and orientation of objects …

In recent years, the task of estimating the 6D pose of object instances and complete scenes,
ie camera localization, from a single input image has received considerable attention. …

Physical forces generated by cells drive morphologic changes during development and can
feedback to regulate cellular phenotypes. Because these phenomena typically occur within …

Spinal muscular atrophy (SMA) is a common neurodegenerative disease that is caused by
deletions or loss-of-function mutations in the Survival of Motor Neuron (SMN) protein. SMN is …

Angiogenesis is a complex morphogenetic process whereby endothelial cells from existing
vessels invade as multicellular sprouts to form new vessels. Here, we have engineered a …