Subacute combined degeneration of the spinal cord following nitrous oxide anesthesia: a systematic review of cases

…, VRN Gunness, D Hersey, N Alshafai… - Clinical Neurology and …, 2018 - Elsevier
Objective Vitamin B12 deficiency can lead to subacute combined degeneration (SCD). Nitrous
oxide (N 2 O) is an anesthetic which oxidizes the cobalt ion of vitamin B12, interfering with …

Surgical approach for suprasellar hemangioblastomas preserving the pituitary stalk: Review of the literature and report of a further case

N Alshafai, R Maduri, M Shail, D Chirchiglia… - Clinical neurology and …, 2018 - Elsevier
Hemangioblastomas (HBLs) are challenging vascular tumours with rare suprasellar
location Surgery is recommended in patients with visual impairment, endocrine disorders or …

Low copy number of the salivary amylase gene predisposes to obesity

…, PH Sudmant, R Dorajoo, MN Al-Shafai… - Nature …, 2014 - nature.com
Common multi-allelic copy number variants (CNVs) appear enriched for phenotypic associations
compared to their biallelic counterparts 1 , 2 , 3 , 4 . Here we investigated the influence …

Practises and controversies in the management of asymptomatic aneurysms: results of an international survey

N Alshafai, O Falenchuk… - British Journal of …, 2015 - Taylor & Francis
Background: Asymptomatic aneurysms that are increasingly discovered on cranial diagnostic
imaging are a growing management dilemma. Large-scale studies have shown that in …

Extreme lateral approach to the craniovertebral junction: an update

NS Alshafai, T Klepinowski - … : Experimental and Clinical Updates for a New …, 2019 - Springer
Introduction:The term ‘extreme lateral approach’ (ELA) was first introduced by Sen and Sekhar
relatively recently (in 1990). Its definition varies and remains controversial, but it generally …

Global differences in the present and future management of cerebral aneurysms

N Alshafai, MD Cusimano, O Falenchuk - World Neurosurgery, 2013 - Elsevier
… Respondents predicted that flow-diversion treatment of aneurysms with the use of stenting
will show large increases and that coiling will show a mild decrease in Europe and North

The high cervical anterolateral retropharyngeal approach

NS Alshafai, VRN Gunness - … : Experimental and Clinical Updates for a …, 2019 - Springer
The first high cervical anterolateral retropharyngeal (HCALR) approach was reported by
Stevenson et al. for a clivus chordoma in 1966. Anterior approaches to the spine have often …

International differences in the management of intracranial aneurysms: implications for the education of the next generation of neurosurgeons

N Alshafai, O Falenchuk, MD Cusimano - Acta neurochirurgica, 2015 - Springer
… More North Americans than those from the rest of the world are of the opinion that
graduating residents are presently competent to perform basic cerebrovascular procedures like …

[HTML][HTML] Investigation of genetic causes in patients with congenital heart disease in qatar: Findings from the Sidra Cardiac Registry

…, A El Jerbi, H Khodjet-El-khil, M Al-Shafai, N Syed… - Genes, 2022 - mdpi.com
Congenital heart disease (CHD) is one of the most common forms of birth defects worldwide,
with a prevalence of 1–2% in newborns. CHD is a multifactorial disease partially caused by …

[HTML][HTML] Microendoscopic Tailored Spine Decompression as a Less-Invasive, Stability-Preserving Surgical Option to Instrumented Correction in Complex Spine …

…, A Eldellaa, A Gigante, M Iacoangeli, NS Alshafai… - World Neurosurgery, 2024 - Elsevier
Objectives The aim of this study was to explore the effectiveness of a less-invasive posterior
spine decompression in complex deformities. We studied the potential advantages of the …