Factors influencing pathologic results after total mesorectal excision for rectal cancer: analysis of consecutive 100 cases

S Hyuk Baik, N Kyu Kim, K Young Lee… - Annals of surgical …, 2008 - Springer
… Upon arrival at the laboratory, the macroscopic judgment of the resected specimen was
evaluated using the definition as described above by a single pathologist (Kim … Nam Kyu Kim MD …

Hypoxia-induced VEGF enhances tumor survivability via suppression of serum deprivation-induced apoptosis

…, JE Jang, CM Kang, HY Chung, ND Kim, KW Kim - Oncogene, 2000 - nature.com
Low oxygen and nutrient depletion play critical roles in tumorigenesis, but little is known
about how they interact to produce tumor survival and tumor malignancy. In the present study, …

Apoptotic activity of ursolic acid may correlate with the inhibition of initiation of DNA replication

…, JW Sung, DK Kim, HY Chung, ND Kim… - … journal of cancer, 2000 - Wiley Online Library
Ursolic acid (UA), a pentacyclic triterpene acid, has been reported to exhibit anti‐tumor
activity. In this study, we investigated the pro‐apoptotic effect of UA on HepG2 human …

Different gene expression profiles between microsatellite instability-high and microsatellite stable colorectal carcinomas

…, K Hye Koh, N Kyu Kim, J Song, E Tak-Bun Liu, H Kim - Oncogene, 2004 - nature.com
Recent molecular genetic studies have revealed that two major types of genomic instabilities,
chromosomal instability (CIN) and microsatellite instability (MSI), exist in colorectal …

Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (HSP90) inhibitors targeting proliferation and angiogenesis

…, K Kim, HH Kim, J Jung, JM Lee, NJ Kim… - Journal of medicinal …, 2012 - ACS Publications
… (19) In addition, we proposed that deguelin binds to the N-terminal ATP-binding pocket of
HSP90 using a structure–function analysis with a docking study of deguelin and HSP90. (19, …

Novel bile acid derivatives induce apoptosis via a p53-independent pathway in human breast carcinoma cells

…, KJ Paik, H Suh, Y Jin, KW Kim, YH Yoo, ND Kim - Cancer letters, 2001 - Elsevier
We have compared the anti-proliferative effects of ursodeoxycholic acid (UDCA), chenodeoxycholic
acid (CDCA) and their derivatives, HS-1183, HS-1199 and HS-1200, on MCF-7 (wild…

Polyplex-releasing microneedles for enhanced cutaneous delivery of DNA vaccine

NW Kim, MS Lee, KR Kim, JE Lee, K Lee… - Journal of controlled …, 2014 - Elsevier
Microneedle (MN)-based DNA vaccines have many advantages over conventional vaccines
administered by hypodermic needles. However, an efficient strategy for delivering DNA …

Anti-inflammatory actions of soluble Ninjurin-1 ameliorate atherosclerosis

S Jeon, TK Kim, SJ Jeong, IH Jung, N Kim, MN Lee… - Circulation, 2020 - Am Heart Assoc
… Oil Red O–stained lesions in en face preparations of whole aortas (n=13 per group; A)
and … most of the experiments with help from TK Kim and Dr SH Park. Drs Jeong, Jung, N. …

Ursolic acid-induced down-regulation of MMP-9 gene is mediated through the nuclear translocation of glucocorticoid receptor in HT1080 human fibrosarcoma cells

…, MT Park, HY Chung, ND Kim, H Sato, M Seiki, KW Kim - Oncogene, 1998 - nature.com
We have previously reported that ursolic acid, a pentacyclic triterpene acid, inhibited the
invasion of HT1080 human fibrosarcoma cells by reducing the expression of matrix …

[HTML][HTML] Dynamic chloroplast genome rearrangement and DNA barcoding for three Apiaceae species known as the medicinal herb “Bang-Poong”

HO Lee, HJ Joh, K Kim, SC Lee, NH Kim… - International journal of …, 2019 - mdpi.com
Three Apiaceae species Ledebouriella seseloides, Peucedanum japonicum, and Glehnia
littoralis are used as Asian herbal medicines, with the confusingly similar common name “Bang…