The clinical use of deep brain stimulation (DBS) is among the most important advances in
the clinical neurosciences in the past two decades. As a surgical tool, DBS can directly …

Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …

Despite the best available medical treatments, many patients continue to be disabled by
neurologic and psychiatric disorders, resulting in a large unmet need. Advances in imaging and …

Magnetic resonance-guided focused ultrasound in combination with intravenously injected
microbubbles has been shown to transiently open the blood–brain barrier, and reduce beta-…

Background Uncontrolled pilot studies have suggested the efficacy of focused ultrasound
thalamotomy with magnetic resonance imaging (MRI) guidance for the treatment of essential …

… low quality (N = 78) and 42% of studies were graded as moderate or high quality (N = 57). …
reported that there was decreased time in the OR (N = 5) as a result of RDH restrictions. …

… With time, the perilesional oedema cleared and the lesion size diminished from a mean
diameter (n=4) of 6·3 mm on the first postoperative day to 4·2 mm at 3 months. The procedures …

… (n = 1 liposomal doxorubicin, n = 4 temozolomide) one day prior to their scheduled
surgical resection. Samples of “sonicated” and “unsonicated” tissue were measured for the …

Focused ultrasound (FUS) is a disruptive medical technology, and its implementation in the
clinic represents the culmination of decades of research. Lying at the convergence of physics…

… Enrolled patients were allocated in an open-label manner to the arm (n = 2) or leg (n = 2)
target group depending on which left-sided limb was weaker. In each group, MRgFUS …