The interpretation of genomic variants has become one of the paramount challenges in the
post-genome sequencing era. In this review we summarize nearly 20 years of research on …

Background Surgery, as part of a multimodal approach, offers the greatest chance of cure
for esophageal cancer. However, esophagectomy is often perceived as having a lasting …

BRCA1 and BRCA2 testing for hereditary breast and ovarian cancer (HBOC) does not
identify all pathogenic variants. Sequencing of 20 complete genes in HBOC patients with …

Intrauterine adhesions (IUAs) are a result of trauma to the basalis layer of the endometrium
and may lead to clinical sequelae such as miscarriage, infertility, and menstrual irregularities. …

… Natasha G Caminsky received the Smith International Surgical Scholarship from the
Cleveland Clinic Florida for travel support to attend the 31st Annual International Colorectal …

Purpose Effective antenatal counseling in congenital diaphragmatic hernia (CDH) relies on
proper measurement of prognostic indices. This quality initiative audited the accuracy of …

We present a prototype software system with sufficient capacity and speed to estimate
radiation exposures in a mass casualty event by counting dicentric chromosomes (DCs) in …

Background Sequencing of both healthy and disease singletons yields many novel and low
frequency variants of uncertain significance (VUS). Complete gene and genome sequencing …

Purpose Low- and middle-income countries (LMICs) have only 19% of the global surgical
workforce yet see 80% of worldwide deaths from noncommunicable diseases. We aimed to …

Objectives With increased bicycle use during the COVID-19 pandemic and growing availability
of bicycle-sharing programs in Montreal, we hypothesize helmet use has decreased. The …