A Third Vaccine Dose in Organ-Transplant Recipients It is known that people receiving
immune suppressive therapy, such as recipients of solid-organ transplants, have a suboptimal …

The liver is the largest solid organ in the body and is critical for metabolic and immune
functions. However, little is known about the cells that make up the human liver and its immune …

This article summarizes strategies to protect the liver from injuries caused by ischemia and
reperfusion. Three different sections (ie, surgical and pharmacologic strategies and gene …

The selection of liver transplant candidates with hepatocellular carcinoma (HCC) relies
mostly on tumor size and number. Instead of relying on these factors, we used poor tumor …

Background & Aims: Tumor necrosis factor (TNF)-α and interleukin (IL)-6 mediate hepatocyte
proliferation in vivo, suggesting that local and systemic inflammatory reactions may trigger …

The European trial investigating normothermic ex vivo liver perfusion (NEVLP) as a
preservation technique for liver transplantation (LT) uses gelofusine, a non–US Food and Drug …

Although livers exhibit only minimal morphologic changes with age, how older livers tolerate
pathologic conditions such as normothermic ischemia is unknown. Young 6‐week‐old mice …

BACKGROUND/AIMS: Fatty livers are increasingly used for transplantation due to the
dramatic organ shortage. While steatosis is an established risk factor for post-operative …

Importance Colorectal cancer is a leading cause of cancer-related death, and nearly 70% of
patients with this cancer have unresectable colorectal cancer liver metastases (CRLMs). …

Background & Aims Radiofrequency ablation (RFA) is an effective treatment for single
hepatocellular carcinoma (HCC) ≤3 cm. Disease recurrence is common, and in some patients …