User profiles for Nigil Haroon

Nigil Haroon, MD, PhD, DM, FRCPC

Associate Professor, University of Toronto. Clinician Scientist, University Health Network
Verified email at uhn.ca
Cited by 18290

Pathogenesis of ankylosing spondylitis—recent advances and future directions

…, E Gracey, MA Brown, RD Inman, N Haroon - Nature Reviews …, 2017 - nature.com
Over the past 5 years, advances in high-throughput techniques and studies involving large
cohorts of patients have led to considerable advances in the identification of novel genetic …

The impact of tumor necrosis factor α inhibitors on radiographic progression in ankylosing spondylitis

N Haroon, RD Inman, TJ Learch… - Arthritis & …, 2013 - Wiley Online Library
Objective To study the effect of tumor necrosis factor α (TNFα) inhibitors on progressive spinal
damage in patients with ankylosing spondylitis (AS). Methods All AS patients meeting the …

[PDF][PDF] American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network 2015 recommendations for the …

…, RD Inman, V Majithia, N Haroon… - Arthritis & …, 2016 - Wiley Online Library
Objective To provide evidence‐based recommendations for the treatment of patients with
ankylosing spondylitis (AS) and nonradiographic axial spondyloarthritis (SpA). Methods A core …

[HTML][HTML] Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1

…, L Appleton, C Farrah, J Lau, N Haroon… - Nature …, 2015 - nature.com
Ankylosing spondylitis (AS) is a common, highly heritable, inflammatory arthritis for which
HLA-B*27 is the major genetic risk factor, although its role in the aetiology of AS remains …

2019 update of the American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network recommendations for …

…, M Dubreuil, D Yu, MA Khan, N Haroon… - Arthritis & …, 2019 - Wiley Online Library
Objective To update evidence‐based recommendations for the treatment of patients with
ankylosing spondylitis ( AS ) and nonradiographic axial spondyloarthritis (SpA). Methods We …

Patients with ankylosing spondylitis have increased cardiovascular and cerebrovascular mortality: a population-based study

NN Haroon, JM Paterson, P Li, RD Inman… - Annals of internal …, 2015 - acpjournals.org
Background: Ankylosing spondylitis (AS) is a chronic inflammatory arthritis affecting the spine
in young adults. It is associated with excess cardiovascular and cerebrovascular morbidity. …

Axial disease in psoriatic arthritis and ankylosing spondylitis: a critical comparison

J Feld, V Chandran, N Haroon, R Inman… - Nature Reviews …, 2018 - nature.com
Ankylosing spondylitis (AS) was first identified in the late 17th century. 250 years later,
inflammatory spine disease was recognized to be one of the patterns of psoriatic arthritis (PsA). …

Impact of rheumatoid arthritis on quality of life

N Haroon, A Aggarwal, A Lawrence, V Agarwal… - Modern …, 2007 - Springer
Quality of life (QOL) of patients affected by various diseases is now recognized as an important
outcome variable. Consenting patients with rheumatoid arthritis (American College of …

Genetic dissection of acute anterior uveitis reveals similarities and differences in associations observed with ankylosing spondylitis

…, RD Inman, P Rahman, N Haroon… - Arthritis & …, 2015 - Wiley Online Library
Objective To use high‐density genotyping to investigate the genetic associations of acute
anterior uveitis (AAU) in patients with and those without ankylosing spondylitis (AS). Methods …

Efficacy and safety of bimekizumab in axial spondyloarthritis: results of two parallel phase 3 randomised controlled trials

…, K Gaffney, LS Gensler, N Haroon… - Annals of the …, 2023 - ard.bmj.com
Objectives Axial spondyloarthritis (axSpA) is a complex disease with diverse manifestations,
for which new treatment options are warranted. BE MOBILE 1 (non-radiographic (nr)-axSpA…