User profiles for Noel Chan
 | Noel ChanAssistant Professor, Department of Medicine, McMaster University Verified email at taari.ca Cited by 2871 |
[HTML][HTML] When and how to use antidotes for the reversal of direct oral anticoagulants: guidance from the SSC of the ISTH
The direct oral anticoagulants (DOACs), which include dabigatran, rivaroxaban, apixaban,
and edoxaban, are licensed for stroke prevention in patients with atrial fibrillation and for …
and edoxaban, are licensed for stroke prevention in patients with atrial fibrillation and for …
COVID-19 coagulopathy, thrombosis, and bleeding
United States alone. SARS-CoV-2 enters cells by binding to the angiotensinconverting
enzyme 2 receptor, which is expressed on respiratory epithelial cells and other cell types, …
enzyme 2 receptor, which is expressed on respiratory epithelial cells and other cell types, …
Prevention of venous thromboembolism in 2020 and beyond
Venous thromboembolism (VTE) is the third most common cause of vascular mortality
worldwide and comprises deep-vein thrombosis (DVT) and pulmonary embolism (PE). In this …
worldwide and comprises deep-vein thrombosis (DVT) and pulmonary embolism (PE). In this …
Direct oral anticoagulants: evidence and unresolved issues
N Chan, M Sobieraj-Teague, JW Eikelboom - The Lancet, 2020 - thelancet.com
Currently licenced direct oral anticoagulants selectively target thrombin (eg, dabigatran) or
coagulation factor Xa (eg, apixaban, betrixaban, edoxaban, and rivaroxaban). Designed to be …
coagulation factor Xa (eg, apixaban, betrixaban, edoxaban, and rivaroxaban). Designed to be …
Syntheses of nicotinamide riboside and derivatives: effective agents for increasing nicotinamide adenine dinucleotide concentrations in mammalian cells
T Yang, NYK Chan, AA Sauve - Journal of medicinal chemistry, 2007 - ACS Publications
A new two-step methodology achieves stereoselective synthesis of β-nicotinamide riboside
and a series of related amide, ester, and acid nucleosides. Compounds were prepared …
and a series of related amide, ester, and acid nucleosides. Compounds were prepared …
Evolving treatments for arterial and venous thrombosis: role of the direct oral anticoagulants
The direct oral anticoagulants (DOACs) represent a major advance in oral anticoagulant
therapy and have replaced the vitamin K antagonists as the preferred treatment for many …
therapy and have replaced the vitamin K antagonists as the preferred treatment for many …
Laboratory measurement of the direct oral anticoagulants
BJ Dale, NC Chan… - British journal of …, 2016 - Wiley Online Library
Direct oral anticoagulants ( DOAC s), including the direct thrombin inhibitor, dabigatran, and
the direct factor Xa ( FX a) inhibitors, rivaroxaban, apixaban and edoxaban, are approved …
the direct factor Xa ( FX a) inhibitors, rivaroxaban, apixaban and edoxaban, are approved …
Peripheral oxygen saturation in older persons wearing nonmedical face masks in community settings
Methods| This was a crossover study in which participants self-measured peripheral oxygen
saturation (SpO2) before, while, and after wearing a mask. The study protocol was approved …
saturation (SpO2) before, while, and after wearing a mask. The study protocol was approved …
Reliability of pubertal self‐assessment in Hong Kong Chinese children
NPT Chan, RYT Sung, APS Kong… - … of paediatrics and …, 2008 - Wiley Online Library
Aim: To validate a Tanner stages self‐assessment questionnaire using gender‐specific line
drawings and brief explanatory text in Chinese. Methods: Design: A cross sectional study …
drawings and brief explanatory text in Chinese. Methods: Design: A cross sectional study …
Antithrombotic agents: new directions in antithrombotic therapy
Recent advances in our understanding of the contribution of thrombin generation to arterial
thrombosis and the role of platelets in venous thrombosis have prompted new treatment …
thrombosis and the role of platelets in venous thrombosis have prompted new treatment …
