Background Registry data on patients with type 1 diabetes mellitus who undergo pancreatic
islet transplantation indicate that only 8 percent are free of the need for insulin therapy at …

Islet transplantation can restore endogenous β-cell function to subjects with type 1 diabetes.
Sixty-five patients received an islet transplant in Edmonton as of 1 November 2004. Their …

Lack of a small animal model of the human hepatitis C virus (HCV) has impeded development
of antiviral therapies against this epidemic infection. By transplanting normal human …

Islet transplantation offers the prospect of good glycemic control without major surgical risks.
After our initial report of successful islet transplantation, we now provide further data on 12 …

Clinical islet transplantation is gaining acceptance as a potential therapy, particularly for
subjects who have labile diabetes or problems with hypoglycemic awareness. The risks of the …

Recent progress in islet isolation from the pancreas of large mammals including man,
accentuated the need for the development of precise and reproducible techniques to assess islet …

A major problem in hepatitis C virus (HCV) immunotherapy or vaccine design is the extreme
variability of the virus. We identified human monoclonal antibodies (mAbs) that neutralize …

The (–) enantiomer of 3′–thiacytidine (lamivudine) has been found to be a potent inhibitor
of hepatitis B virus (HBV) and human immunodeficiency virus (HIV) replication. Mutation of …

This report summarizes a recent meeting cosponsored by the American Society of Transplant
Physicians and the American Association for the Study of Liver Diseases to formulate …

The current model of liver graft allocation in place in the United States favors transplantation
of patients with small hepatocellular carcinomas (HCCs) within the Milan criteria (a single …